(3S-cis)-(+)-Tetrahydro-3-isopropyl-7a-methylpyrrolo[2,1-b]oxazol-5(6H)-one

• Catalog No.: 334235
• CAS Number: 98203-44-2
• M. F.: C10H17NO2
• M. W.: 183.24748
• Purity: 95%

SYNONYMS

• Title: (3S-顺)-(+)-四氢-3-异丙基-7a-甲基吡咯并[2,1-b]噁唑-5(6H)-酮
• IUPAC name: (3S,7aR)-7a-methyl-3-(propan-2-yl)-hexahydropyrrolo[2,1-b][1,3]oxazol-5-one
• IUPAC Traditional name: (3S,7aR)-3-isopropyl-7a-methyl-tetrahydropyrrolo[2,1-b][1,3]oxazol-5-one

DATABASE IDS

• PubChem SID: 24860069
• CAS Number: 98203-44-2
• MDL Number: MFCD00467212

PROPERTIES

• Empirical Formula (Hill Notation): C10H17NO2
• Purity: 95%
• Boiling Point: 70 °C/0.4 mmHg(lit.)
• Density: 1.027 g/mL at 25 °C(lit.)
• Flash Point: 58 °C
• Flash Point: 136.4 °F
• Optical Rotation: [α]27/D +90°, c = 2.8 in ethanol
• Refractive Index: n20/D 1.473(lit.)
• GHS Signal Word: Warning
• GHS Hazard statements: H226-H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
• GHS Precautionary statements: P261-P305 + P351 + P338
• RID/ADR: UN 1224 3/PG 3
• Risk Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazard Class: 3
• UN Number: 1224
• Packing Group: 3
• German water hazard class: 3

DETAILS

Description (English)

Application
Chiral bicyclic lactams such as this are useful templates for the asymmetric synthesis of a variety of natural and unnatural products.1 High levels of asymmetric induction have been obtained in cycloadditions,2,3 alkylations,4,5,6 conjugate additions,7,8 annulations,9 and dihydroxylations.10
Packaging
5 g in glass bottle

Description (简体中文)

Application
像这样的手性双环内酰胺类化合物是不对称合成许多天然和非天然产物的有用模板。1已在以下反应中实现了高水平的不对称诱导：环加成、2,3烷基化、4,5,6共轭加成、7,8成环、9以及双羟基化。10
包装
5 g in glass bottle