N-Benzoyl-(2R,3S)-3-phenylisoserine

• Catalog No.: 444375
• CAS Number: 132201-33-3
• M. F.: C16H15NO4
• M. W.: 285.2946
• Purity: 98%

SYNONYMS

• Title: N-苯甲酰基-(2R,3S)-3-苯基异丝氨酸
• IUPAC name: (2R,3S)-2-hydroxy-3-phenyl-3-(phenylformamido)propanoic acid
• IUPAC Traditional name: (2R,3S)-2-hydroxy-3-phenyl-3-(phenylformamido)propanoic acid

DATABASE IDS

• PubChem SID: 24868119
• MDL Number: MFCD00274633
• CAS Number: 132201-33-3

PROPERTIES

• Linear Formula: C6H5CONHCH(C6H5)CH(OH)CO2H
• Purity: 98%
• Melting Point: 169-172 °C(lit.)
• Optical Rotation: [α]20/D -40°, c = 1.0 in ethanol
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P261-P305 + P351 + P338
• Risk Statements: 36/37/38
• Safety Statements: 26-36
• German water hazard class: 3

DETAILS

Description (English)

Packaging
500 mg in glass bottle
Application
The presence of this chiral side chain has proven to be essential for the biological activity of taxol,1,2,3 one of the most promising anticancer agents being investigated.4,5 The challenging synthesis of taxol has stimulated interest in the attachment of the C-13 side chain to naturally derived taxanes like baccatin III.6,7,8

Description (简体中文)

包装
500 mg in glass bottle
Application
已经证明，该手性侧链的存在对于紫杉醇的生物活性至关重要，1,2,3 紫杉醇是目前正在研究的最有潜力的抗癌药之一。4,5 紫杉醇复杂的合成过程已经引起人们对在天然衍生紫杉烷类（例如，巴卡亭 III）上附接 C-13 侧链的关注。6,7,8