Baicalein

• Catalog No.: 465119
• CAS Number: 491-67-8
• M. F.: C15H10O5
• M. W.: 270.2369
• Purity: 98%

SYNONYMS

• Title: 三羟黄酮
• IUPAC name: 5,6,7-trihydroxy-2-phenyl-4H-chromen-4-one
• IUPAC Traditional name: baicalein
• Synonyms: 5,6,7-Trihydroxyflavone; 5,6,7-三羟基黄酮

DATABASE IDS

• Beilstein Number: 272683
• PubChem SID: 24870246
• MDL Number: MFCD00017459
• CAS Number: 491-67-8

PROPERTIES

• Empirical Formula (Hill Notation): C15H10O5
• Purity: 98%
• Gene Information: mouse ... Hexa(15211)rat ... Alox15(81639), Alox5(25290)
• Melting Point: 256-271 °C(lit.)
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P261-P305 + P351 + P338
• Risk Statements: 36/37/38
• Safety Statements: 26-36
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
The flavonoid component of Nepalese and Sino-Japanese crude drugs.1,2 Baicalein, a major flavone of Scutellariae baicalensis, inhibits the 12-lipoxygenase (12-LOX) pathway of arachidonic acid metabolism, which inhibits cancer cell proliferation and induces apoptosis.
Packaging
100, 500 mg in glass bottle

Description (简体中文)

Biochem/physiol Actions
尼泊尔和中日天然药物中的类黄酮组分。1,2三羟黄酮（黄芩的主要黄酮），可抑制花生四烯酸代谢的 12-脂氧合酶 (12-LOX) 途径，从而抑制癌细胞增殖并诱导癌细胞凋亡。
包装
100, 500 mg in glass bottle