| Item |
Information |
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Drug Groups
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approved; nutraceutical |
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Description
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The 4-carboxyaldehyde form of vitamin B 6 which is converted to pyridoxal phosphate which is a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. [PubChem] |
| Indication |
Pyridoxal is one of the natural forms available of vitamin B6, therefore, it is used for nutritional supplementation and for treating dietary shortage or imbalances. |
| Pharmacology |
Pyridoxal principally in the form of the coenzyme pyridoxal 5'-phosphate, is involved in a wide range of biochemical reactions, including the metabolism of amino acids and glycogen, the synthesis of nucleic acids, hemogloblin, sphingomyelin and other sphingolipids, and the synthesis of the neurotransmitters serotonin, dopamine, norepinephrine and gamma-aminobutyric acid (GABA). |
| Toxicity |
Oral LD50 Rat: 2150 mg/kg, Oral LD50 Mouse: 1800 mg/kg |
| Affected Organisms |
| • |
Humans and other mammals |
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| External Links |
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