N-Acetylprocainamide hydrochloride

• Catalog No.: 205656
• CAS Number: 34118-92-8
• M. F.: C15H24ClN3O2
• M. W.: 313.82296
• Purity: 99%

SYNONYMS

• Title: N-乙酰普鲁卡因胺 盐酸盐
• IUPAC name: N-[2-(diethylamino)ethyl]-4-acetamidobenzamide hydrochloride
• IUPAC Traditional name: NAPA hydrochloride
• Synonyms: N-Acetylnovocainamide hydrochloride; N-乙酰普卡胺 盐酸盐; Acecainide hydrochloride; NAPA; 乙酰卡尼 盐酸盐

DATABASE IDS

• CAS Number: 34118-92-8
• PubChem SID: 24852214
• MDL Number: MFCD00012501
• EC Number: 251-831-2

PROPERTIES

• Linear Formula: 4-(CH3CONH)C6H4CONHCH2CH2N(C2H5)2·HCl
• Purity: 99%
• Melting Point: 184-186 °C(lit.)
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Packaging
1, 5 g in glass bottle
Biochem/physiol Actions
Class III antiarrhythmic. Increases the duration of the action potential by decreasing the delayed outward potassium current, slightly decreasing the calcium current, and slightly depressing the inward rectifier potassium current. This is the active metabolite of procainamide that does not induce systemic lupus erythematosus.

Description (简体中文)

包装
1, 5 g in glass bottle
Biochem/physiol Actions
III 类抗心律失常药。通过降低延时的外向钾电流、稍微降低钙电流以及稍微抑制内向整流钾电流来增大动作电位的持续时间。这是普鲁卡因胺的活性代谢物，不会导致全身性红斑狼疮。