1,2,3,4-Tetrahydro-9H-pyrido[3,4-b]indole

• Catalog No.: 300764
• CAS Number: 16502-01-5
• M. F.: C11H12N2
• M. W.: 172.22638
• Purity: 98%

SYNONYMS

• Title: 1,2,3,4-四氢-9H-吡啶并[3,4-b]吲哚
• IUPAC name: 1H,2H,3H,4H,9H-pyrido[3,4-b]indole
• IUPAC Traditional name: tryptoline
• Synonyms: THBC; Tryptoline; Tetrahydronorharmane; 1,2,3,4-四氢-β-咔啉; 2,3,4,9-四氢-1H-吡啶并(3,4-b)吲哚; Noreleagnine; Tetrahydronorharman

DATABASE IDS

• MDL Number: MFCD00004954
• PubChem SID: 24857939
• CAS Number: 16502-01-5

PROPERTIES

• Empirical Formula (Hill Notation): C11H12N2
• Purity: 98%
• Gene Information: rat ... Htr2a(29595), Htr2c(25187)
• Melting Point: 206-208 °C(lit.)
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P261-P305 + P351 + P338
• Risk Statements: 36/37/38
• Safety Statements: 26-36
• German water hazard class: 3

DETAILS

Description (English)

Packaging
1, 5 g in glass bottle
Application

• Reactant for synthesis of the indolyl-β-carboline alkaloid eudistomin U via IBX mediated room temperature oxidative aromatization1
• Reactant for preparation of neuroprotective HDAC6 inhibitors2
• Reactant for preparation of aminofuranopyrimidines as EGFR and Aurora A kinase inhibitors3
• Reactant for preparation of inhibitors of CDK44
• Reactant for preparation of tetrahydrocarboline derivatives of as human 5-HT5A receptor ligands5
• Reactant for preparation of 5-(diaminomethyl)-2,4-aminopyrimidines as dihydrofolate reductase inhibitors and antibacterial agents6
Employed in alkaloid synthesis and in studies on neurodegenerative diseases.
Other Notes
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. 300764.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Description (简体中文)

包装
1, 5 g in glass bottle
Application

• Reactant for synthesis of the indolyl-β-carboline alkaloid eudistomin U via IBX mediated room temperature oxidative aromatization1
• Reactant for preparation of neuroprotective HDAC6 inhibitors2
• Reactant for preparation of aminofuranopyrimidines as EGFR and Aurora A kinase inhibitors3
• Reactant for preparation of inhibitors of CDK44
• Reactant for preparation of tetrahydrocarboline derivatives of as human 5-HT5A receptor ligands5
• Reactant for preparation of 5-(diaminomethyl)-2,4-aminopyrimidines as dihydrofolate reductase inhibitors and antibacterial agents6
用于生物碱的合成以及用于研究神经退行性疾病。
Other Notes
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. 300764.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.