2-Fluoroaniline

• Catalog No.: F3401
• CAS Number: 348-54-9
• M. F.: C6H6FN
• M. W.: 111.1169432
• Purity: ≥99%

SYNONYMS

• IUPAC name: 2-fluoroaniline
• IUPAC Traditional name: 2-fluoroaniline
• Synonyms: 1-Amino-2-fluorobenzene

DATABASE IDS

• MDL Number: MFCD00007642
• CAS Number: 348-54-9
• PubChem SID: 24894844
• Beilstein Number: 1524219
• EC Number: 206-478-9

PROPERTIES

• Linear Formula: FC6H4NH2
• Purity: ≥99%
• Boiling Point: 182-183 °C(lit.)
• Density: 1.151 g/mL at 25 °C(lit.)
• Flash Point: 60 °C
• Flash Point: 140 °F
• Melting Point: -29 °C(lit.)
• Refractive Index: n20/D 1.544(lit.)
• GHS Signal Word: Danger
• GHS Hazard statements: H226-H302-H315-H318-H335
• European Hazard Symbols: Harmful (Xn)
• Personal Protective Equipment: Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
• GHS Precautionary statements: P261-P280-P305 + P351 + P338
• RID/ADR: UN 2941 6.1/PG 3
• Risk Statements: 22-37/38-41
• Safety Statements: 26-39
• Hazard Class: 6.1
• UN Number: 2941
• Packing Group: 3
• German water hazard class: 3

DETAILS

Description (English)

Packaging
25, 100, 500 g in glass bottle
Biochem/physiol Actions
The metabolism and excretion of the xenobiotic compound 2-fluoroaniline is important due to human exposure in manufacturing. It is found to be very efficiently metabolized, primarily by 4-hydroxylation with subsequent sulfate or glucuronide formation. N-Acetylation is also observed. At least 80% of the dose is excreted in the urine within 24 hr.1 2-Fluoroaniline exerts its nephrotoxic effect through 4-hyroxylation and subsequent p-benzoquinonimine formation.2

Description (简体中文)

包装
25, 100, 500 g in glass bottle
Biochem/physiol Actions
The metabolism and excretion of the xenobiotic compound 2-fluoroaniline is important due to human exposure in manufacturing. It is found to be very efficiently metabolized, primarily by 4-hydroxylation with subsequent sulfate or glucuronide formation. N-Acetylation is also observed. At least 80% of the dose is excreted in the urine within 24 hr.1 2-Fluoroaniline exerts its nephrotoxic effect through 4-hyroxylation and subsequent p-benzoquinonimine formation.2