Diethyl (N-methoxy-N-methylcarbamoylmethyl)phosphonate

• Catalog No.: 362433
• CAS Number: 124931-12-0
• M. F.: C8H18NO5P
• M. W.: 239.205981
• Purity: 96%

SYNONYMS

• Title: N-甲氧基-N-甲羰基甲基膦酸二乙酯
• IUPAC name: diethyl {[methoxy(methyl)carbamoyl]methyl}phosphonate
• IUPAC Traditional name: diethyl [methoxy(methyl)carbamoyl]methylphosphonate
• Synonyms: Diethylphosphonoacetic acid N-methyl-N-methoxyamide; N-Methoxy-N-methyl-2-(diethyl phosphono)acetamide; Diethyl N-methoxy-N-methylphosphonoacetamide; N-Methoxy-N-methyl-phosphonoacetamide diethyl ester

DATABASE IDS

• MDL Number: MFCD00134233
• CAS Number: 124931-12-0
• Beilstein Number: 1875865
• PubChem SID: 24862312

PROPERTIES

• Linear Formula: CH3ON(CH3)COCH2P(O)(OC2H5)2
• Purity: 96%
• Boiling Point: 90 °C/17 mmHg(lit.)
• Density: 1.163 g/mL at 25 °C(lit.)
• Flash Point: 110 °C
• Flash Point: 230 °F
• Refractive Index: n20/D 1.455(lit.)
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
• GHS Precautionary statements: P261-P305 + P351 + P338
• Risk Statements: 36/37/38
• Safety Statements: 26-36
• German water hazard class: 3

DETAILS

Description (English)

Application
Wittig carbonylating reagent.7
Reactant for:
• Preparation of ring-expanded bryostatin analogs as antitumor agents1
• Asymmertic synthesis of pinnatoxins A and G via diastereoselective Ireland-Claisen rearrangement, ring closing metathesis, and cyclization2
• Rh2(II)-catalyzed nitro-group migration reactions3
• Stereoselective synthesis of cyclohexanones via phase transfer catalyzed double addition reactions4
• Stereoselective synthesis of (+)-polyrhacitide A via aldol reaction, Horner-Wardsworth-Emmons reaction, Evans acetal intramolecular oxa-Michael reaction and diastereoselective syn reduction reaction as the key steps5
• Preparation of substituted furans via olefin cross-metathesis6
Packaging
1, 5 g in glass bottle

Description (简体中文)

Application
Wittig 羰基化试剂7
Reactant for:
• Preparation of ring-expanded bryostatin analogs as antitumor agents1
• Asymmertic synthesis of pinnatoxins A and G via diastereoselective Ireland-Claisen rearrangement, ring closing metathesis, and cyclization2
• Rh2(II)-catalyzed nitro-group migration reactions3
• Stereoselective synthesis of cyclohexanones via phase transfer catalyzed double addition reactions4
• Stereoselective synthesis of (+)-polyrhacitide A via aldol reaction, Horner-Wardsworth-Emmons reaction, Evans acetal intramolecular oxa-Michael reaction and diastereoselective syn reduction reaction as the key steps5
• Preparation of substituted furans via olefin cross-metathesis6
包装
1, 5 g in glass bottle