(R)-(-)-1,1′-Binaphthyl-2,2′-diyl hydrogenphosphate

• Catalog No.: 248932
• CAS Number: 39648-67-4
• M. F.: C20H13O4P
• M. W.: 348.288581
• Purity: ≥98%

SYNONYMS

• Title: R-联萘酚磷酸酯
• IUPAC name: 13-hydroxy-12,14-dioxa-13λ^5-phosphapentacyclo[13.8.0.0^2,^1^1.0^3,^8.0^1^8,^2^3]tricosa-1(15),2(11),3,5,7,9,16,18,20,22-decaen-13-one
• IUPAC Traditional name: 13-hydroxy-12,14-dioxa-13λ^5-phosphapentacyclo[13.8.0.0^2,^1^1.0^3,^8.0^1^8,^2^3]tricosa-1(15),2(11),3,5,7,9,16,18,20,22-decaen-13-one
• Synonyms: (R)-(-)-1,1′-Binaphthalene-2,2′-diyl hydrogen phosphate; (R)-(-)-1,1′-联萘-2,2′-二基磷酸氢酯; (R)-4-Hydroxydinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-oxide; (R)-4-羟基二萘并[2,1-d:1′,2′-f][1,3,2]二噁磷杂庚英-4-氧化物

DATABASE IDS

• CAS Number: 39648-67-4
• MDL Number: MFCD00010045
• PubChem SID: 24854961
• Beilstein Number: 4713363

PROPERTIES

• Empirical Formula (Hill Notation): C20H13O4P
• Purity: ≥98%
• Optical Rotation: [α]20/D -605°, c = 1.35 in methanol
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P261-P305 + P351 + P338
• Risk Statements: 36/37/38
• Safety Statements: 26-36
• German water hazard class: 3

DETAILS

Description (English)

Packaging
1, 5 g in glass bottle
Application
A chiral ligand used in hydrocarboxylation reactions.1 Complexes with rhodium and mediates the asymmetric dipolar cycloaddition of diazo compounds.2 A number of racemic amines which have proven difficult to separate have been resolved with this chiral acid.3 Palladium derivatives have been used in asymmetric hydrocarboxylations,4 and rhodium derivatives have been used in dipolar cycloadditions.5
Used in a chiral Bronsted acid catalyzed enantoselective Mannich reaction.
Protocols & Applications
Reductive Amination using BINOL-Derived Chiral Phosphoric Acids

Description (简体中文)

包装
1, 5 g in glass bottle
Application
用于手性布朗斯特酸催化的不对称 Mannich 反应。
用于氢羧基化反应的手性配体。1与铑络合并调节重氮化合物的不对称偶极环加成反应。2许多已证明难以分离的外消旋胺可以使用该手性酸进行分离。3钯衍生物已用于不对称氢羧基化反应，4并且铑衍生物已用于偶极环加成反应。5
Protocols & Applications
Reductive Amination using BINOL-Derived Chiral Phosphoric Acids