Benzhydryl chloride, polymer-bound

• Catalog No.: 572616
• M. F.: C13H10Cl
• M. W.: 201.6715

SYNONYMS

• Title: 聚合物键合型二苯氯甲烷

DATABASE IDS

• MDL Number: MFCD03702610
• PubChem SID: 24880649

PROPERTIES

• Crosslinking: 1 % cross-linked with divinylbenzene
• Extent of Labeling: 1.6-2.2 mmol/g loading
• Particle Size: 100-200 mesh
• European Hazard Symbols: Irritant (Xi)
• Risk Statements: 43
• Safety Statements: 36/37
• German water hazard class: 1

DETAILS

Description (English)

Packaging
25 g in glass bottle
Application
This electrophilic resin is used for the attachment of amines alcohols, sulfamates, thiols and phenols using the Fmoc strategy. This resin is an intermediate between the Merrifield resin and the trityl chloride resin in term of acid lability. The carbocation formed during the cleavage reaction is more stable than Merrifield resin but less stable than the trityl chloride resins. The substituents on the benzhydryl chloride can be chosen in order to obtain a less acid labile resin (2-chloro) or a more acid labile resin (4-Methyl) than the benzhydryl chloride resin.

Description (简体中文)

包装
25 g in glass bottle
Application
此亲电树脂用于采用 Fmoc 法附接胺、醇、氨基磺酸酯、硫醇和酚。此树脂的酸不稳定性介于氯甲基树脂和三苯甲基氯树脂之间。裂解反应过程中，此树脂形成的碳正离子的稳定性高于氯甲基树脂，而低于三苯甲基氯树脂。可选择二苯氯甲烷上的取代基，以获得酸稳定性比二苯氯甲烷树脂更低（2-氯）或更高（4-甲基）的树脂。