Home > Compound List > Product Information
Ethyl (4-fluorobenzoyl)acetate_Molecular_structure_CAS_1999-00-4)
Click picture or here to close

Ethyl (4-fluorobenzoyl)acetate

Catalog No. 146293 Name Sigma Aldrich
CAS Number 1999-00-4 Website http://www.sigmaaldrich.com
M. F. C11H11FO3 Telephone 1-800-521-8956
M. W. 210.2016432 Fax
Purity Email
Storage Chembase ID: 100522

SYNONYMS

Title
(4-氟苯甲酰)乙酸乙酯
IUPAC name
ethyl 3-(4-fluorophenyl)-3-oxopropanoate
IUPAC Traditional name
ethyl 3-(4-fluorophenyl)-3-oxopropanoate
Synonyms
Ethyl 3-(4-fluorophenyl)-3-oxopropionate
(p-Fluorobenzoyl)acetic acid ethyl ester
对氟苯甲酰乙酸乙酯
4-Fluoro-β-oxobenzenepropanoic acid ethyl ester
Ethyl 4-fluorobenzoylacetate

DATABASE IDS

CAS Number 1999-00-4
PubChem SID 24848775
MDL Number MFCD03093631

PROPERTIES

Linear Formula FC6H4COCH2CO2C2H5
Boiling Point 117-120 °C(lit.)
Density 1.174 g/mL at 25 °C(lit.)
Refractive Index n20/D 1.5040(lit.)
MSDS Link Download
Personal Protective Equipment Eyeshields, Gloves
German water hazard class 3

DETAILS

Description (English)
Packaging
1, 5 g in glass bottle
Application
Reactant used as a precursor in:
• Condensation reactions with diamines via C-C bond cleavage for synthesis of benzimidazoles and perimidines1 for possible use as antimalarial treatments2
• Base-promoted domino Michael addition / cyclization / elimination reactions for synthesis of hydroxybenzophenones3
• Oxidative cross-coupling with indoles via dioxygen activation4
• Cyclization of keto esters for synthesis of pyrones5
• Lewis base catalyzed hydrosilylation for synthesis of α-acetoxy β-amino acid derivatives6
• Conia-ene reactions for synthesis of methylenecyclopentane derivatives7
Description (简体中文)
包装
1, 5 g in glass bottle
Application
Reactant used as a precursor in:
• Condensation reactions with diamines via C-C bond cleavage for synthesis of benzimidazoles and perimidines1 for possible use as antimalarial treatments2
• Base-promoted domino Michael addition / cyclization / elimination reactions for synthesis of hydroxybenzophenones3
• Oxidative cross-coupling with indoles via dioxygen activation4
• Cyclization of keto esters for synthesis of pyrones5
• Lewis base catalyzed hydrosilylation for synthesis of α-acetoxy β-amino acid derivatives6
• Conia-ene reactions for synthesis of methylenecyclopentane derivatives7

REFERENCES