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Flavopiridol

Catalog No. DB03496 Name DrugBank
CAS Number 131740-09-5 Website http://www.ualberta.ca/
M. F. C21H20ClNO5 Telephone (780) 492-3111
M. W. 401.8402 Fax (780) 492-1071
Purity Email david.wishart@ualberta.ca
Storage Chembase ID: 3170

SYNONYMS

IUPAC name
2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-methylpiperidin-4-yl]-4H-chromen-4-one
IUPAC Traditional name
flavopiridol
Synonyms
CPB
Flavo
flavopiridol
HMR-1275
Flavopiridol hydrochloride
Alvocidib

DATABASE IDS

PubChem CID 5287969
CAS Number 131740-09-5
PubChem SID 46507266

PROPERTIES

DETAILS

Description (English)
Item Information
Drug Groups experimental; investigational
Description Flavopiridol is a synthetic flavonoid based on an extract from an Indian plant for the potential treatment of cancer. It works by inhibiting cyclin-dependent kinases, arresting cell division and causing apoptosis in non-small lung cancer cells.
Indication Investigated for use/treatment in esophageal cancer, leukemia (lymphoid), lung cancer, liver cancer, and lymphoma (unspecified).

REFERENCES