7-Fluoro-4-hydroxycoumarin

• Catalog No.: 732982
• CAS Number: 2145-27-9
• M. F.: C9H5FO3
• M. W.: 180.1326032

SYNONYMS

• IUPAC name: 7-fluoro-4-hydroxy-2H-chromen-2-one
• IUPAC Traditional name: 7-fluoro-4-hydroxychromen-2-one
• Synonyms: 7-Fluoro-4-hydroxy-2H-chromen-2-one; 7-Fluoro-4-hydroxy-1(2H)-benzopyran-2-one

DATABASE IDS

• MDL Number: MFCD11845381
• CAS Number: 2145-27-9

PROPERTIES

• Empirical Formula (Hill Notation): C9H5FO3
• Melting Point: 220-225 °C
• GHS Signal Word: Warning
• GHS Hazard statements: H302
• European Hazard Symbols: Harmful (Xn)
• Risk Statements: 22
• German water hazard class: 3

DETAILS

Description (English)

Packaging
250 mg in glass bottle
Application
Reactant for:
• Enantioselective synthesis of polycyclic coumarins via in situ formed primary amine-imine-catalyzed asymmetric Michael addition to cyclic enones1
• Preparation of dicoumarol analogs as inhibitors of human NAD(P)H quinone oxidoreductase-1 (NQO1) as agents active against human pancreatic and colon cancer cells2
• Imidazolidinecarboxylic acid-catalyzed asymmetric Michael reaction with unsaturated ketones in a highly atom-economic catalytic one-step formation of optically active warfarin anticoagulant3
• Asymmetric synthesis of functionalized α-keto esters and their hemiketal and hemiaminal derivatives via direct Michael addition with unsaturated α-keto esters catalyzed by bisoxazoline-copper(II) complexes4

Description (简体中文)

包装
250 mg in glass bottle
Application
Reactant for:
• Enantioselective synthesis of polycyclic coumarins via in situ formed primary amine-imine-catalyzed asymmetric Michael addition to cyclic enones1
• Preparation of dicoumarol analogs as inhibitors of human NAD(P)H quinone oxidoreductase-1 (NQO1) as agents active against human pancreatic and colon cancer cells2
• Imidazolidinecarboxylic acid-catalyzed asymmetric Michael reaction with unsaturated ketones in a highly atom-economic catalytic one-step formation of optically active warfarin anticoagulant3
• Asymmetric synthesis of functionalized α-keto esters and their hemiketal and hemiaminal derivatives via direct Michael addition with unsaturated α-keto esters catalyzed by bisoxazoline-copper(II) complexes4