5-Nitro-2-oxindole

• Catalog No.: 653683
• CAS Number: 20870-79-5
• M. F.: C8H6N2O3
• M. W.: 178.14484
• Purity: 97%

SYNONYMS

• Title: 5-硝基吲哚-2-酮
• IUPAC name: 5-nitro-2,3-dihydro-1H-indol-2-one
• IUPAC Traditional name: 5-nitro-1,3-dihydroindol-2-one
• Synonyms: 5-Nitro-1,3-dihydroindole-2-one; NSC 25199; NSC 99066; 5-硝基-1,3-二氢-2H-吲哚-2-酮

DATABASE IDS

• MDL Number: MFCD00456999
• CAS Number: 20870-79-5
• PubChem SID: 24883978

PROPERTIES

• Empirical Formula (Hill Notation): C8H6N2O3
• Purity: 97%
• Melting Point: 233-236 °C
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H317-H319-H335
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Faceshields, Gloves
• GHS Precautionary statements: P261-P280-P305 + P351 + P338
• Risk Statements: 36/37/38-43
• Safety Statements: 26-36/37
• German water hazard class: 3

DETAILS

Description (English)

Packaging
1, 5 g in glass bottle
Application

• Reactant for synthesis of 3-[4-(amino/methylsulfonyl)phenyl]methylene-indolin-2-one derivatives as novel COX-1/2 and 5-LOX inhibitors1
• Reactant for preparation of Aurora kinase inhibitors2
• Reactant for synthesis of 3-substituted 2-indolinone RET inhibitors3
• Reactant for synthesis of 4-azachromeno[2,3-b]indol-11(6H)-ones and derivatives as analogs of ellipticine4
• Reactant for preparation of [18F]fluorobenzylidene-indolinone as possible tyrosine kinase inhibitor for PET tumor imaging5
• Reactant for preparation of 3-substituted indolin-2-ones as neuroprotective and toxic agents6

Description (简体中文)

包装
1, 5 g in glass bottle
Application

• Reactant for synthesis of 3-[4-(amino/methylsulfonyl)phenyl]methylene-indolin-2-one derivatives as novel COX-1/2 and 5-LOX inhibitors1
• Reactant for preparation of Aurora kinase inhibitors2
• Reactant for synthesis of 3-substituted 2-indolinone RET inhibitors3
• Reactant for synthesis of 4-azachromeno[2,3-b]indol-11(6H)-ones and derivatives as analogs of ellipticine4
• Reactant for preparation of [18F]fluorobenzylidene-indolinone as possible tyrosine kinase inhibitor for PET tumor imaging5
• Reactant for preparation of 3-substituted indolin-2-ones as neuroprotective and toxic agents6