N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8a,9S)-6′-methoxy-9-cinchonanyl]thiourea

• Catalog No.: 690481
• CAS Number: 852913-16-7
• M. F.: C29H28F6N4OS
• M. W.: 594.6142392
• Purity: ≥89.0%

SYNONYMS

• Title: N-[3,5-双(三氟甲基)苯基]-N′-[(8a,9S)-6′-甲氧基-9-金鸡宁]硫脲
• IUPAC name: 1-[3,5-bis(trifluoromethyl)phenyl]-3-[(S)-[(2S,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl](6-methoxyquinolin-4-yl)methyl]thiourea
• IUPAC Traditional name: 1-[3,5-bis(trifluoromethyl)phenyl]-3-[(S)-[(2S,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl](6-methoxyquinolin-4-yl)methyl]thiourea
• Synonyms: 1-[3,5-Bis(trifluoromethyl)phenyl)-3-{(S)(6-methoxy-4-quinolinyl)-[(2S,4S,5R)-5-vinyl-1-aza-bicyclo[2.2.2]oct-2-yl]methyl}thiourea; epi-N-喹啉基-N′-双(3,5-三氟甲基)苯硫脲; epi-N-Quinyl-N′-bis(3,5-trifluoromethyl)phenylthiourea; 1-[3,5-双(三氟甲基)苯基)-3-{(S)(6-甲氧基-4-喹啉基)-[(2S,4S,5R)-5-乙烯基-1-氮杂-二环[2.2.2]辛-2-基]甲基}硫脲

DATABASE IDS

• CAS Number: 852913-16-7
• MDL Number: MFCD16875670

PROPERTIES

• Empirical Formula (Hill Notation): C29H28F6N4OS
• Purity: ≥89.0%
• Purity: 90%
• Optical Rotation: [α]/D -110.0±10.0°, c = 1 in chloroform
• GHS Signal Word: Danger
• GHS Hazard statements: H301
• European Hazard Symbols: Toxic (T)
• Personal Protective Equipment: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
• GHS Precautionary statements: P301 + P310
• Risk Statements: 25
• Safety Statements: 45
• German water hazard class: 3

DETAILS

Description (English)

Application
Highly enantioselective conjugate addition of nitromethane to chalcones using bifunctional cinchona organocatalysts.1,2
Packaging
250 mg in glass bottle

Description (简体中文)

Application
采用双官能化金鸡纳有机催化剂，进行硝基甲烷的高度对映选择性共轭加成反应，生成查耳酮1,2
包装
250 mg in glass bottle