(7R,10S)-(+)-1-Aza-10-isopropyl-8-oxa-4-thiabicyclo[5.3.0]-2-decanone

• Catalog No.: 667587
• M. F.: C10H17NO2S
• M. W.: 215.31248
• Purity: 97%

SYNONYMS

• Title: (7R,10S)-(+)-1-氮杂-10-异丙基-8-氧杂-4-硫杂双环[5.3.0]-2-癸酮
• IUPAC name: (3S,9aR)-3-(propan-2-yl)-hexahydro-2H-[1,3]oxazolo[3,2-d][1,4]thiazepin-5-one
• IUPAC Traditional name: (3S,9aR)-3-isopropyl-hexahydro-[1,3]oxazolo[3,2-d][1,4]thiazepin-5-one
• Synonyms: Gleason 手性助剂; Gleason chiral auxiliary

DATABASE IDS

• MDL Number: MFCD08276884
• PubChem SID: 24884924

PROPERTIES

• Empirical Formula (Hill Notation): C10H17NO2S
• Purity: 97%
• Melting Point: 142-146 °C
• German water hazard class: 3

DETAILS

Description (English)

Application
This chiral lactam auxiliary has been successfully employed in the stereocontrolled synthesis of all carbon quaternary centers. The unique methodology developed by Gleason allows for the creation of either antipode of the product using a single isomer of the auxiliary.1
Gleason Chiral Auxiliary
Packaging
1 g in glass bottle

Description (简体中文)

Application
这种手性内酰胺助剂已成功用于立体控制性合成所有季碳中心。通过 Gleason 开发的独特方法，可利用该助剂的一种异构体生成该产品的两种对映体。1
Gleason Chiral Auxiliary
包装
1 g in glass bottle