(R)-(+)-2-Methyl-CBS-oxazaborolidine solution

• Catalog No.: 674656
• CAS Number: 112022-83-0
• M. F.: C18H20BNO
• M. W.: 277.1685

SYNONYMS

• Title: (R)-(+)-2-甲基-CBS-噁唑硼烷 溶液
• IUPAC name: (3aR)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole
• IUPAC Traditional name: (3aR)-1-methyl-3,3-diphenyl-tetrahydropyrrolo[1,2-c][1,3,2]oxazaborole
• Synonyms: (R)-1-甲基,3,3-二苯基-四氢-吡咯并(1,2-c)(1,3,2)噁唑硼烷; (R)-Tetrahydro-1-methyl-3,3-diphenyl-1H,3H-pyrrolo[1,2-c][1,3,2]oxazaborole; α,α-Diphenyl-D-prolinolmethylboronic acid cyclamide ester; (R)-1-Methyl,3,3-diphenyl-tetrahydro-pyrrolo(1,2-c)(1,3,2)oxazaborole; (R)-四氢-1-甲基-3,3-二苯基-1H,3H-吡咯并[1,2-c][1,3,2]噁唑硼烷; (R)-3-甲基-CBS-氧杂硼啶

DATABASE IDS

• CAS Number: 112022-83-0
• MDL Number: MFCD00078440
• PubChem SID: 24885228

PROPERTIES

• Concentration: 1 M in THF
• Empirical Formula (Hill Notation): C18H20BNO
• Density: 0.942 g/mL at 25 °C
• Flash Point: -17 °C
• Flash Point: 1.4 °F
• Optical Rotation: [α]22/D +76.8°, c = 1 in toluene
• Refractive Index: n20/D 1.4602
• GHS Signal Word: Danger
• GHS Hazard statements: H225-H319-H335
• European Hazard Symbols: Flammable (F)
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
• GHS Precautionary statements: P210-P261-P305 + P351 + P338
• RID/ADR: UN 2056 3/PG 2
• Risk Statements: 11-19-36/37
• Safety Statements: 16-26
• Supplemental Hazard Statements: May form explosive peroxides.
• Hazard Class: 3
• UN Number: 2056
• Packing Group: 2
• German water hazard class: 3

DETAILS

Description (English)

Packaging
5, 25 mL in glass bottle
Application
CBS Catalysts for Asymmetric Reduction and Asymmetric Synthesis
The CBS (Corey-Bakshi-Shibata) oxazaborolidine catalyst has been used in the asymmetric reduction of prochiral ketones. Other applications include the enantioselective synthesis of α-hydroxy acids, α-amino acids, C2 symmetrical ferrocenyl diols, and propargyl alcohols.

Description (简体中文)

包装
5, 25 mL in glass bottle
Application
CBS Catalysts for Asymmetric Reduction and Asymmetric Synthesis
CBS (Corey-Bakshi-Shibata) 噁唑硼烷催化剂已被用于前手性酮的非对称性还原。其他应用包括 α-羟基酸、α-氨基酸、C2 对称二茂铁二醇以及炔丙醇的对映选择性合成。