Acetylthiomethyl-diphenylphosphine borane complex

• Catalog No.: 670359
• CAS Number: 446822-71-5
• M. F.: C15H18BOPS
• M. W.: 288.152581
• Purity: ≥98.0%

SYNONYMS

• Title: 乙酰基硫甲基-硼烷二苯基膦复合物
• IUPAC name: 1-{[(diphenylphosphanyl)methyl]sulfanyl}ethan-1-one borane
• IUPAC Traditional name: 1-{[(diphenylphosphanyl)methyl]sulfanyl}ethanone borane

DATABASE IDS

• CAS Number: 446822-71-5

PROPERTIES

• Empirical Formula (Hill Notation): C15H18BOPS
• Purity: ≥98.0%
• Melting Point: 52-55 °C
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P261-P305 + P351 + P338
• Risk Statements: 36/37/38
• Safety Statements: 26
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Packaging
1 g in glass bottle
250 mg in glass bottle
Legal Information
Sold under license for research and development purposes only. US Patent 6,974,884 and related patents apply
Application

• Traceless Staudinger ligation reagent with borane protecting group.
• The borane group stabilizes the phosphine against oxidation and can be easily removed with mild basic or acidic conditions to yield the active phosphine.1
• After reaction with an azide, the phosphine is eliminated in the presence of water to yield a native amide bond.2
• Used in the synthesis of cyclic peptides.2

Description (简体中文)

包装
1 g in glass bottle
250 mg in glass bottle
Legal Information
授权后方可销售，仅供研发使用。美国专利 6,974,884 和相关专利申请
Application

• Traceless Staudinger ligation reagent with borane protecting group.
• The borane group stabilizes the phosphine against oxidation and can be easily removed with mild basic or acidic conditions to yield the active phosphine.1
• After reaction with an azide, the phosphine is eliminated in the presence of water to yield a native amide bond.2
• Used in the synthesis of cyclic peptides.2