(R)-α,α-Bis[3,5-bis(trifluoromethyl)phenyl]-2-pyrrolidinemethanol trimethylsilyl ether

• Catalog No.: 677213
• CAS Number: 908303-26-4
• M. F.: C24H23F12NOSi
• M. W.: 597.5118584

SYNONYMS

• Title: (R)-α,α-双[3,5-双(三氟甲基)苯基]-2-吡咯烷甲醇三甲基硅基醚
• IUPAC name: (2R)-2-{bis[3,5-bis(trifluoromethyl)phenyl][(trimethylsilyl)oxy]methyl}pyrrolidine
• IUPAC Traditional name: (2R)-2-{bis[3,5-bis(trifluoromethyl)phenyl][(trimethylsilyl)oxy]methyl}pyrrolidine
• Synonyms: (R)-2-[(Bis(3,5-bis(trifluoromethyl)phenyl)]trimethylsilanyloxy)methyl]pyrrolidine; (R)-2-[(Bis(3,5-bis(trifluoromethyl)phenyl)]trimethylsilyloxy)methyl]pyrrolidine; (R)-2-[(双(3,5-双(三氟甲基)苯基)]三甲基硅烷氧基)甲基]吡咯烷; (R)-α,α-Bis[3,5-bis(trifluoromethyl)phenyl]prolinol trimethylsilyl ether; (R)-α,α-双[3,5-双(三氟甲基)苯基]脯氨醇三甲基硅醚; (R)-2-[(双(3,5-双(三氟甲基)苯基)]三甲基甲硅氧基)甲基]吡咯烷

DATABASE IDS

• PubChem SID: 24885357
• MDL Number: MFCD09750448
• CAS Number: 908303-26-4

PROPERTIES

• Empirical Formula (Hill Notation): C24H23F12NOSi
• Grade: technical grade
• Optical Purity: enantiomeric excess: ≥99.0% (HPLC)
• Flash Point: >110 °C
• Flash Point: >230 °F
• Melting Point: 46-55 °C
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P261-P305 + P351 + P338
• Risk Statements: 36/37/38
• Safety Statements: 26
• German water hazard class: 3

DETAILS

Description (简体中文)

包装
1, 5 g in glass bottle
Application
Catalyst involved in:
• Cyclocondensation of enals with methylenepyrrolidines1
• Organocatalytic additions of β-ketosulfoxides to conjugated aldehydes2
• Organocatalytic aza-Michael reactions3,4
• Stereoselective propargylic alkylation of propargylic esters with aldehydes5
• Epoxidation or aziridination of α,β-unsaturated aldehydes and Feist-Benary reactions of 1,3-dicarbonyls6
Protocols & Applications
Asymmetric a-Functionalization of Aldehydes using J??rgensen's Organocatalysts

Description (English)

Packaging
1, 5 g in glass bottle
Application
Catalyst involved in:
• Cyclocondensation of enals with methylenepyrrolidines1
• Organocatalytic additions of β-ketosulfoxides to conjugated aldehydes2
• Organocatalytic aza-Michael reactions3,4
• Stereoselective propargylic alkylation of propargylic esters with aldehydes5
• Epoxidation or aziridination of α,β-unsaturated aldehydes and Feist-Benary reactions of 1,3-dicarbonyls6
Protocols & Applications
Asymmetric a-Functionalization of Aldehydes using J?rgensen's Organocatalysts