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N-Boc-4-piperidineacetaldehyde_Molecular_structure_CAS_142374-19-4)
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N-Boc-4-piperidineacetaldehyde

Catalog No. 680214 Name Sigma Aldrich
CAS Number 142374-19-4 Website http://www.sigmaaldrich.com
M. F. C12H21NO3 Telephone 1-800-521-8956
M. W. 227.30004 Fax
Purity 97% Email
Storage Chembase ID: 140870

SYNONYMS

Title
4-(2-氧代乙基)哌啶-1-羧酸叔丁酯
IUPAC name
tert-butyl 4-(2-oxoethyl)piperidine-1-carboxylate
IUPAC Traditional name
tert-butyl 4-(2-oxoethyl)piperidine-1-carboxylate
Synonyms
1-(tert-butyloxycarbonyl)-piperidine-4-acetaldehyde
tert-Butyl 4-(formylmethyl)piperidine-1-carboxylate
4-(2-Oxoethyl)piperidine-1-carboxylic acid, tert-butyl ester

DATABASE IDS

PubChem SID 24885547
MDL Number MFCD03425258
CAS Number 142374-19-4

PROPERTIES

Empirical Formula (Hill Notation) C12H21NO3
Purity 97%
Flash Point >110 °C
Flash Point >230 °F
Melting Point 38-42 °C
GHS Pictograms GHS07
GHS Signal Word Warning
GHS Hazard statements H315-H319-H335
European Hazard Symbols Irritant Irritant (Xi)
MSDS Link Download
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
GHS Precautionary statements P261-P305 + P351 + P338
Risk Statements 36/37/38
Safety Statements 26
German water hazard class 3

DETAILS

Description (English)
Application
Building block employed in a synthesis of (S)-quinuclidine-2-carboxylic acid.7 Substrate used in an enanioselective organo-catalytic α-vinylation reaction.8
Reactant for synthesis of:
• Pim-1 inhibitors1
• Selective GPR119 agonists for type II diabetes2,3Reactant for:
• α-arylation of aldehydes4
• Enantioselective α-benzylation of aldehydes via photoredox organocatalysis5
• Enantioselective α-triflouromethylation of aldehydes6
Packaging
1 g in glass bottle
Description (简体中文)
Application
用于合成 (S)-奎宁环-2-羧酸的结构单元。7用于不对称有机催化 α-乙烯化反应的底物。8
Reactant for synthesis of:
• Pim-1 inhibitors1
• Selective GPR119 agonists for type II diabetes2,3Reactant for:
• α-arylation of aldehydes4
• Enantioselective α-benzylation of aldehydes via photoredox organocatalysis5
• Enantioselective α-triflouromethylation of aldehydes6
包装
1 g in glass bottle

REFERENCES