Di-(4-chlorobenzyl)azodicarboxylate

• Catalog No.: 680850
• CAS Number: 916320-82-6
• M. F.: C16H12Cl2N2O4
• M. W.: 367.18348
• Purity: 97%

SYNONYMS

• Title: 双(4-氯苄基)偶氮二甲酸酯
• IUPAC name: N-({[(4-chlorophenyl)methoxy]carbonyl}imino)[(4-chlorophenyl)methoxy]formamide
• IUPAC Traditional name: N-({[(4-chlorophenyl)methoxy]carbonyl}imino)[(4-chlorophenyl)methoxy]formamide
• Synonyms: DCAD; Bis(4-chlorobenzyl)azodicarboxylate; 偶氮二甲酸二(对氯苄基)酯

DATABASE IDS

• CAS Number: 916320-82-6
• PubChem SID: 24885598

PROPERTIES

• Empirical Formula (Hill Notation): C16H12Cl2N2O4
• Purity: 97%
• Melting Point: 108-112 °C
• GHS Signal Word: Warning
• GHS Hazard statements: H317
• European Hazard Symbols: Irritant (Xi)
• GHS Precautionary statements: P280
• Risk Statements: 43
• Safety Statements: 36/37
• German water hazard class: 3

DETAILS

Description (English)

Application
Di-(4-chlorobenzyl)azodicarboxylate (DCAD) is a novel, stable, solid alternative to DEAD and DIAD for a variety of Mitsunobu couplings giving a readily separable hydrazine byproduct that can be recycled.4
Reactant for preparation of:
• Amino thioesters via guanidine-catalyzed biomimetic enantioselective decarboxylative Mannich and amination reactions of malonic acid half thioesters1
• Hydroacylation reaction of aldehydes in Ionic liquid (IL) medium2
• DCAD (di-p-chlorobenzyl azodicarboxylate) for Mitsunobu coupling reactions3,4
Packaging
1, 10 g in glass bottle

Description (简体中文)

Application
双(4-氯苄基)偶氮二甲酸酯 (DCAD) 是 DEAD 和 DIAD 的新型稳定固体替代物，可用于多种 Mitsunobu 偶联反应，生成易于分离并且可回收利用的副产物肼。4
Reactant for preparation of:
• Amino thioesters via guanidine-catalyzed biomimetic enantioselective decarboxylative Mannich and amination reactions of malonic acid half thioesters1
• Hydroacylation reaction of aldehydes in Ionic liquid (IL) medium2
• DCAD (di-p-chlorobenzyl azodicarboxylate) for Mitsunobu coupling reactions3,4
包装
1, 10 g in glass bottle