1,1-Dimethylbiguanide hydrochloride

• Catalog No.: D150959
• CAS Number: 1115-70-4
• M. F.: C4H12ClN5
• M. W.: 165.62458
• Purity: 97%

SYNONYMS

• Title: 甲福明 盐酸盐
• IUPAC name: 1-carbamimidamido-N,N-dimethylmethanimidamide hydrochloride
• IUPAC Traditional name: metformin hydrochloride
• Synonyms: 二甲双胍; Metformin

DATABASE IDS

• MDL Number: MFCD00012582
• PubChem SID: 24893460
• EC Number: 214-230-6
• CAS Number: 1115-70-4

PROPERTIES

• Linear Formula: NH2C(=NH)NHC(=NH)N(CH3)2 · HCl
• Purity: 97%
• Melting Point: 223-226 °C(lit.)
• GHS Signal Word: Warning
• GHS Hazard statements: H302-H315-H319
• European Hazard Symbols: Harmful (Xn)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P305 + P351 + P338
• Risk Statements: 22-36/38
• RTECS: DU1800000
• Safety Statements: 26-36
• German water hazard class: 3

DETAILS

Description (English)

Frequently Asked Questions
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Biochem/physiol Actions
Metformin is an antidiabetic agent that reduces blood glucose levels and improves insulin sensitivity. Its metabolic effects, including the inhibition of hepatic gluconeogenesis, are mediated at least in part by activation of the LKB1-AMPK (AMP-activated protein kinase) pathway. Activation of this pathway also appears to be involved in the antiproliferative and proapoptotic actions of metformin in cancer cell lines.
Packaging
5 g in glass bottle

Description (简体中文)

Frequently Asked Questions
Live Chat and Frequently Asked Questions are available for this Product.
Biochem/physiol Actions
甲福明是一种抗糖尿病药，可降低血糖水平，提高胰岛素灵敏度。其代谢作用（包括抑制肝脏糖异生作用）至少部分是通过激活 LKB1-AMPK（AMP-活化蛋白激酶）通路进行介导。该通路的激活也涉及到癌细胞系中甲福明的抗增殖和促凋亡作用。
包装
5 g in glass bottle