(R)-(-)-VAPOL hydrogenphosphate

• Catalog No.: 675512
• CAS Number: 871130-18-6
• M. F.: C40H25O4P
• M. W.: 600.597861

SYNONYMS

• Title: (R)-(-)-VAPOL 磷酸氢酯
• IUPAC name: 17-hydroxy-3,31-diphenyl-16,18-dioxa-17λ^5-phosphaheptacyclo[17.12.0.0^2,^1^5.0^5,^1^4.0^8,^1^3.0^2^0,^2^9.0^2^1,^2^6]hentriaconta-1(31),2,4,6,8,10,12,14,19,21,23,25,27,29-tetradecaen-17-one
• IUPAC Traditional name: 17-hydroxy-3,31-diphenyl-16,18-dioxa-17λ^5-phosphaheptacyclo[17.12.0.0^2,^1^5.0^5,^1^4.0^8,^1^3.0^2^0,^2^9.0^2^1,^2^6]hentriaconta-1(31),2,4,6,8,10,12,14,19,21,23,25,27,29-tetradecaen-17-one
• Synonyms: (R)-2,2′-Diphenyl-3,3′-biphenanthryl-4,4′-diyl phosphate; (R)-VAPOL phosphoric acid; (R)-VAPOL 磷酸; 18-Hydroxy-8,9-diphenyl-diphenanthro[4,3-d:3′,4′-f][1,3,2]dioxaphosphepin-18-oxide; (R)-2,2′-二苯基-3,3′-联菲-4,4′-二基磷酸酯; 18-羟基-8,9-二苯基-联菲并[4,3-d:3′,4′-f][1,3,2]二噁磷杂庚英-18-氧化物

DATABASE IDS

• CAS Number: 871130-18-6
• PubChem SID: 24885284
• MDL Number: MFCD09265084

PROPERTIES

• Empirical Formula (Hill Notation): C40H25O4P
• German water hazard class: 3

DETAILS

Description (English)

Application
Useful chiral Bronsted acid catalyst in the addition of sulfonamides to Boc-activated aryl imines.6
Catalyst involved in:
• Desymmetrization of meso-aziridines1
• Asymmetric aza-Darzens aziridine synthesis2
• Enantioselective ring-opening of mono-and bicyclic N-acyl meso aziridines3
• Condensation of aldehydes with amino benzenesulfonamides4
• Pictet-Spengler reactions5
Packaging
100, 500 mg in glass bottle
Protocols & Applications
Reductive Amination using BINOL-Derived Chiral Phosphoric Acids

Description (简体中文)

Application
磺胺加成到 Boc-活化芳基亚胺反应中的手性布朗斯特酸催化剂。6
Catalyst involved in:
• Desymmetrization of meso-aziridines1
• Asymmetric aza-Darzens aziridine synthesis2
• Enantioselective ring-opening of mono-and bicyclic N-acyl meso aziridines3
• Condensation of aldehydes with amino benzenesulfonamides4
• Pictet-Spengler reactions5
包装
100, 500 mg in glass bottle
Protocols & Applications
Reductive Amination using BINOL-Derived Chiral Phosphoric Acids