(-)-DIP-Chloride™

• Catalog No.: 317020
• CAS Number: 85116-37-6
• M. F.: C20H34BCl
• M. W.: 320.74796

SYNONYMS

• IUPAC name: chlorobis[(1R,2S,3R,5R)-2,6,6-trimethylbicyclo[3.1.1]heptan-3-yl]borane
• IUPAC Traditional name: chlorobis[(1R,2S,3R,5R)-2,6,6-trimethylbicyclo[3.1.1]heptan-3-yl]borane
• Synonyms: (-)-Ipc2BCl; (-)-B-二异松蒎基氯硼烷; (-)-B-Chlorodiisopinocampheylborane

DATABASE IDS

• Beilstein Number: 5937756
• PubChem SID: 24859060
• CAS Number: 85116-37-6
• MDL Number: MFCD00074807

PROPERTIES

• Empirical Formula (Hill Notation): C20H34BCl
• Flash Point: 110 °C
• Flash Point: 230 °F
• Melting Point: 52-56 °C(lit.)
• GHS Signal Word: Danger
• GHS Hazard statements: H314
• European Hazard Symbols: Corrosive (C)
• Personal Protective Equipment: Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
• GHS Precautionary statements: P280-P305 + P351 + P338-P310
• RID/ADR: UN 3261 8/PG 2
• Risk Statements: 34
• Safety Statements: 26-36/37/39-45
• Hazard Class: 8
• UN Number: 3261
• Packing Group: 2
• German water hazard class: 3

DETAILS

Description (English)

Application
Both (+)- and (-)-DIP-chloride are used for asymmetric reduction of prochiral ketones1,2 and for the preparation of β-amino alcohols.2,3
Reagent used for an enantioselective reduction of (chloroacetyl) benzofurans to chlorohydrins which serve as intermediates for the corresponding epoxides and aminoalcohols. For a short paper on the preparation of DIP halides and their use in stereoselective reductions see Chem. Commun. 1053 (1994).
Packaging
5, 25, 100 g in glass bottle
Legal Information
DIP-Chloride is a trademark of Sigma-Aldrich Co. LLC

Description (简体中文)

Application
(+)- 和 (-)-DIP-氯化物均可用于前手性酮的不对称还原反应1,2和 β-氨基醇的制备。2,3
用于(氯乙酰基)苯并呋喃不对称还原反应的试剂，生成的氯代醇可用作对应环氧化物和氨基醇的中间体。关于 DIP 卤化物的制备以及他们在立体选择性还原反应中用途的论文，请参见 Chem. Commun. 1053 (1994)。
包装
5, 25, 100 g in glass bottle
法律信息
DIP-Chloride 商标 Sigma-Aldrich Co. LLC