4-Cyanophenylboronic acid

• Catalog No.: 521418
• CAS Number: 126747-14-6
• M. F.: C7H6BNO2
• M. W.: 146.93904

SYNONYMS

• Title: 4-氰基苯硼酸
• IUPAC name: (4-cyanophenyl)boronic acid
• IUPAC Traditional name: 4-cyanophenylboronic acid
• Synonyms: 4-Cyanobenzeneboronic acid; (p-Cyanophenyl)boronic acid; 4-Cyanophenylboric acid

DATABASE IDS

• CAS Number: 126747-14-6
• MDL Number: MFCD01318968
• PubChem SID: 24874205

PROPERTIES

• Linear Formula: NCC6H4B(OH)2
• Melting Point: >350 °C(lit.)
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• German water hazard class: 3

DETAILS

Description (English)

Other Notes
Contains varying amounts of anhydride
Packaging
1 g in glass bottle
10 g in poly bottle
Application
Reactant involved in:
• Oxidative hydroxylation1
• Trifluoromethylation2
• 1,4-Addition reactions3Precursor in the synthesis of inhibitors such as:
• Tpl2 kinase inhibitors4
• P2X7 antagonists used in the treatment of pain5
Reagent used for
• Palladium-catalyzed arylation Suzuki-Miyaura cross-coupling in water
• Ruthenium catalyzed direct arylation of benzylic sp3 carbons of acyclic amines with arylboronates
• Ligand-free copper-catalyzed coupling of nitro arenes with arylboronic acids
• Ferric perchlorate-promoted reaction of fullerenes with various arylboronic acids to give fullerenyl boronic esters
• Phosphine-free Suzuki-Miyaura cross-coupling
• Palladacycles as effective catalysts for multicomponent reaction with allylpalladium-intermediates
• Chan-Lam-type Cu-catalyzed S-arylation of thiols
• Regioselective cross-coupling reactions under modfied Suzuki and Still cross-coupling reactions with Copper catalysis
• Metal-free biaryl coupling in dimethyl carbonate as a solventReagent used for Preparation of
• Himbacine analogs as thrombin receptor antagonists and potential antiplatelet agents
• Trisulfonated calixarene upper-rim sulfonamido and their complexation with trimethyllysine epigenetic mark
• Antimalarial compounds via Suzuki cross-coupling
• Deoxyuridine derivatives

Description (简体中文)

Other Notes
含有不定量的酸酐
包装
1 g in glass bottle
10 g in poly bottle
Application
Reactant involved in:
• Oxidative hydroxylation1
• Trifluoromethylation2
• 1,4-Addition reactions3Precursor in the synthesis of inhibitors such as:
• Tpl2 kinase inhibitors4
• P2X7 antagonists used in the treatment of pain5
Reagent used for
• Palladium-catalyzed arylation Suzuki-Miyaura cross-coupling in water
• Ruthenium catalyzed direct arylation of benzylic sp3 carbons of acyclic amines with arylboronates
• Ligand-free copper-catalyzed coupling of nitro arenes with arylboronic acids
• Ferric perchlorate-promoted reaction of fullerenes with various arylboronic acids to give fullerenyl boronic esters
• Phosphine-free Suzuki-Miyaura cross-coupling
• Palladacycles as effective catalysts for multicomponent reaction with allylpalladium-intermediates
• Chan-Lam-type Cu-catalyzed S-arylation of thiols
• Regioselective cross-coupling reactions under modfied Suzuki and Still cross-coupling reactions with Copper catalysis
• Metal-free biaryl coupling in dimethyl carbonate as a solventReagent used for Preparation of
• Himbacine analogs as thrombin receptor antagonists and potential antiplatelet agents
• Trisulfonated calixarene upper-rim sulfonamido and their complexation with trimethyllysine epigenetic mark
• Antimalarial compounds via Suzuki cross-coupling
• Deoxyuridine derivatives