4-Isoquinolineboronic acid

• Catalog No.: 707929
• CAS Number: 192182-56-2
• M. F.: C9H8BNO2
• M. W.: 172.97632

SYNONYMS

• Title: 4-异喹啉硼酸
• IUPAC name: (isoquinolin-4-yl)boronic acid
• IUPAC Traditional name: isoquinolin-4-ylboronic acid
• Synonyms: 异喹啉-4-硼酸; Isoquinolin-4-ylboronic acid; Isoquinoline-4-boronic acid

DATABASE IDS

• CAS Number: 192182-56-2
• MDL Number: MFCD03412093

PROPERTIES

• Empirical Formula (Hill Notation): C9H8BNO2
• Melting Point: 230-234 °C
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P261-P305 + P351 + P338
• Risk Statements: 36/37/38
• Safety Statements: 26
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

General description
May contain varying amounts of anhydride
Packaging
1, 5 g in glass bottle
Application
Reactant for:
• Preparation of selective steroid-11β-hydroxylase (CYP11B1) inhibitors for treatment of cortisol dependent diseases1
• Preparation of tetrabutylammonium trifluoroborates2
• Preparation of heteroaryl substituted tetrahydropyrroloijquinolinone derivatives as aldosterone synthase inhibitors3
• Synthesis of aminoarylpyridazines as selective CB2 agonists for treatment of inflammatory pain4
• Preparation of acyl substituted indoles via palladium-catalyzed domino coupling/carbonylation/Suzuki coupling of dibromoethenylanilines5
• Synthesis of antagonists of bacterial quorum sensing6
• Preparation of potassium heteroaryl trifluoroborates from boronic acids and their use as coupling partners with various aryl and heteroaryl halides in Suzuki-Miyaura cross-coupling reactions7

Description (简体中文)

General description
可能含不定量的酸酐
包装
1, 5 g in glass bottle
Application
Reactant for:
• Preparation of selective steroid-11β-hydroxylase (CYP11B1) inhibitors for treatment of cortisol dependent diseases1
• Preparation of tetrabutylammonium trifluoroborates2
• Preparation of heteroaryl substituted tetrahydropyrroloijquinolinone derivatives as aldosterone synthase inhibitors3
• Synthesis of aminoarylpyridazines as selective CB2 agonists for treatment of inflammatory pain4
• Preparation of acyl substituted indoles via palladium-catalyzed domino coupling/carbonylation/Suzuki coupling of dibromoethenylanilines5
• Synthesis of antagonists of bacterial quorum sensing6
• Preparation of potassium heteroaryl trifluoroborates from boronic acids and their use as coupling partners with various aryl and heteroaryl halides in Suzuki-Miyaura cross-coupling reactions7