Isopropylmagnesium chloride lithium chloride complex solution

• Catalog No.: 656984
• M. F.: C3H7Cl2LiMg
• M. W.: 145.23968

SYNONYMS

• Title: 异丙基氯化镁氯化锂络合物 溶液
• IUPAC name: lithium(1+) ion chloro(propan-2-yl)magnesium chloride
• IUPAC Traditional name: lithium(1+) ion chloro(isopropyl)magnesium chloride
• Synonyms: Turbo Grignard

DATABASE IDS

• MDL Number: MFCD07784514
• PubChem SID: 24884252

PROPERTIES

• Concentration: 1.3 M in THF
• Linear Formula: (CH3)2CHMgCl · LiCl
• Density: 0.951 g/mL at 25 °C
• Flash Point: -17 °C
• Flash Point: 1.4 °F
• GHS Signal Word: Danger
• GHS Hazard statements: H225-H314-H335
• European Hazard Symbols: Flammable (F)
• European Hazard Symbols: Corrosive (C)
• Personal Protective Equipment: Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
• GHS Precautionary statements: P210-P261-P280-P305 + P351 + P338-P310
• RID/ADR: UN 3399 4.3/PG 2
• Risk Statements: 11-14/15-19-34-37
• Safety Statements: 16-26-36/37/39-43-45
• Supplemental Hazard Statements: May form explosive peroxides., Reacts violently with water.
• Hazard Class: 4.3
• UN Number: 3399
• Packing Group: 2
• German water hazard class: 3

DETAILS

Description (English)

Application
Reagent used with CH3MgCl/LiCl to affect magnesium-halogen exchange on unprotected aryl carboxylic acids.14
Reagent for Selective MetalationsUsed for:
• Preparation of functionalized acyclic alkenyl magnesium reagents/preparation of 1,2-diketones1
• Preparation of cyclic alkenyl and dienyl magnesium reagents2
• Preparation of functionalized triazenes/preparation of carbazoles3
• Regioselective functionalization of trisubstituted pyridines4
• Electrophilic amination for preparation of amines5
• Preparation of Grignards reagents in the presence of masked ketones and aldehydes (using readily deprotectable silylated cyanohydrins)6
• Preparation of Benzylic Grignards via Sulfur-Magnesium exchange7
• Functionalization via I-Mg Exchange of unprotected aromatic and heteroaromatic carboxylic acids8
• Functionalization via I-Mg Exchange of unprotected imidazoles9
• Pyridyne formation10
• Functionalization of cyclopentene derivatives11
• Preparation of 2,3-functionalized furans, benzofurans, and thiophenes12
• Stereoselective synthesis of substituted cyclopropanes13
Packaging
4×25, 100, 800 mL in Sure/Seal™
Legal Information
Product of Rockwood Lithium

Description (简体中文)

Application
Reagent used with CH3MgCl/LiCl to affect magnesium-halogen exchange on unprotected aryl carboxylic acids.14
Reagent for Selective MetalationsUsed for:
• Preparation of functionalized acyclic alkenyl magnesium reagents/preparation of 1,2-diketones1
• Preparation of cyclic alkenyl and dienyl magnesium reagents2
• Preparation of functionalized triazenes/preparation of carbazoles3
• Regioselective functionalization of trisubstituted pyridines4
• Electrophilic amination for preparation of amines5
• Preparation of Grignards reagents in the presence of masked ketones and aldehydes (using readily deprotectable silylated cyanohydrins)6
• Preparation of Benzylic Grignards via Sulfur-Magnesium exchange7
• Functionalization via I-Mg Exchange of unprotected aromatic and heteroaromatic carboxylic acids8
• Functionalization via I-Mg Exchange of unprotected imidazoles9
• Pyridyne formation10
• Functionalization of cyclopentene derivatives11
• Preparation of 2,3-functionalized furans, benzofurans, and thiophenes12
• Stereoselective synthesis of substituted cyclopropanes13
包装
4×25, 100, 800 mL in Sure/Seal™
Legal Information
Product of Rockwood Lithium