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6-Aminoindole

Catalog No. 630721 Name Sigma Aldrich
CAS Number 5318-27-4 Website http://www.sigmaaldrich.com
M. F. C8H8N2 Telephone 1-800-521-8956
M. W. 132.16252 Fax
Purity 97% Email
Storage Chembase ID: 16359

SYNONYMS

Title
6-氨基吲哚
IUPAC name
1H-indol-6-amine
IUPAC Traditional name
1H-indol-6-amine
Synonyms
Indol-6-ylamine
NSC 82379

DATABASE IDS

CAS Number 5318-27-4
PubChem SID 24882337
MDL Number MFCD02093959

PROPERTIES

Empirical Formula (Hill Notation) C8H8N2
Purity 97%
Melting Point 75-79 °C
GHS Pictograms GHS07
GHS Signal Word Warning
GHS Hazard statements H302-H315-H319-H335
European Hazard Symbols Harmful Harmful (Xn)
MSDS Link Download
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
GHS Precautionary statements P261-P305 + P351 + P338
Risk Statements 22-36/37/38
Safety Statements 26-36
Storage Temperature -20°C
German water hazard class 3

DETAILS

Description (English)
Packaging
1, 5 g in glass bottle
Application
Reactant for preparation of:
• Inhibitors of mammalian target of rapamycin (mTOR ) protein1
• Inhibitors of the AcrAB-TolC efflux pump2
• Inhibitors of Gli1-mediated transcription in the Hedgehog pathway3
• Potent DNA-topoisomerase II poisons and anti-MDR agents4
• Protein kinase C θ (PKCθ) inhibitors5
• Piperidine carboxamide as transient receptor potential cation channel subfamily V member 1 (TRPV1) antagonists6
• Potent and selective blockers of the Nav1.8 sodium channel as potential analgesics for the treatment of neuropathic and inflammatory pain7
• 5,6-fused heteroaromatic ureas as TRPV1 antagonists8
• Allosteric enhancers of the A3 adenosine receptor9
• Human liver glycogen phosphorylase (HLGP) inhibitors for the treatment of type 2 diabetes10
Description (简体中文)
包装
1, 5 g in glass bottle
Application
Reactant for preparation of:
• Inhibitors of mammalian target of rapamycin (mTOR ) protein1
• Inhibitors of the AcrAB-TolC efflux pump2
• Inhibitors of Gli1-mediated transcription in the Hedgehog pathway3
• Potent DNA-topoisomerase II poisons and anti-MDR agents4
• Protein kinase C θ (PKCθ) inhibitors5
• Piperidine carboxamide as transient receptor potential cation channel subfamily V member 1 (TRPV1) antagonists6
• Potent and selective blockers of the Nav1.8 sodium channel as potential analgesics for the treatment of neuropathic and inflammatory pain7
• 5,6-fused heteroaromatic ureas as TRPV1 antagonists8
• Allosteric enhancers of the A3 adenosine receptor9
• Human liver glycogen phosphorylase (HLGP) inhibitors for the treatment of type 2 diabetes10

REFERENCES