2-Methoxyethyl chloroformate

• Catalog No.: 592293
• CAS Number: 628-12-6
• M. F.: C4H7ClO3
• M. W.: 138.54958

SYNONYMS

• Title: 2-甲氧基氯甲酸乙酯
• IUPAC name: 2-methoxyethyl chloroformate
• IUPAC Traditional name: 2-methoxyethyl chloroformate
• Synonyms: Chloroformic acid 2-methoxyethyl ester; 2-Methoxyethyl carbonochloridate; (2-Methoxyethoxy)carbonyl chloride; (Chloro)(2-methoxyethoxy)methanone

DATABASE IDS

• CAS Number: 628-12-6
• EC Number: 211-026-9
• PubChem SID: 24881382
• MDL Number: MFCD00058932

PROPERTIES

• Linear Formula: CH3OCH2CH2OCOCl
• Boiling Point: 157-158 °C(lit.)
• Density: 1.192 g/mL at 25 °C(lit.)
• Flash Point: 58 °C
• Flash Point: 136.4 °F
• Refractive Index: n20/D 1.4200(lit.)
• GHS Signal Word: Danger
• GHS Hazard statements: H226-H314
• European Hazard Symbols: Corrosive (C)
• Personal Protective Equipment: Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
• GHS Precautionary statements: P280-P305 + P351 + P338-P310
• RID/ADR: UN 2920 8/PG 2
• Risk Statements: 34
• Safety Statements: 26-36/37/39-45
• Storage Temperature: 2-8°C
• Hazard Class: 8
• UN Number: 2920
• Packing Group: 2
• German water hazard class: 3

DETAILS

Description (English)

Packaging
5, 25, 250 mL in glass bottle
Application
Reactant for:
• Preparation of N-bridged bicyclic sulfonamides as inhibitors of γ-secretase1
• Preparation of dimethoxyethyl azodicarboxylate via amidation/oxidation and application to Mitsunobu reaction2
• Regioselective, stereoselective, and kinetically-controlled nickel-catalyzed cyanoesterification of allenes chloroformates and TMSCN3
• Preparation of amino carboxamidobenzothiazoles as Lck inhibitors4
• Preparation of nonracemic spirooxindoles using a stereoselective three-component coupling reaction as the key step and using acylation reactions to add structural diversity5

Description (简体中文)

包装
5, 25, 250 mL in glass bottle
Application
Reactant for:
• Preparation of N-bridged bicyclic sulfonamides as inhibitors of γ-secretase1
• Preparation of dimethoxyethyl azodicarboxylate via amidation/oxidation and application to Mitsunobu reaction2
• Regioselective, stereoselective, and kinetically-controlled nickel-catalyzed cyanoesterification of allenes chloroformates and TMSCN3
• Preparation of amino carboxamidobenzothiazoles as Lck inhibitors4
• Preparation of nonracemic spirooxindoles using a stereoselective three-component coupling reaction as the key step and using acylation reactions to add structural diversity5