Diethyl azodicarboxylate solution

• Catalog No.: 11627
• CAS Number: 1972-28-7
• M. F.: C6H10N2O4
• M. W.: 174.1546

SYNONYMS

• Title: 偶氮二甲酸二乙酯 溶液
• IUPAC name: N-[(ethoxycarbonyl)imino]ethoxyformamide
• IUPAC Traditional name: diethyl azodicarboxylate
• Synonyms: Unifoam AZ-AE 200; Diethoxycarbonyldiazene solution; NSC 679015; Diethyl azodiformate solution; DEAD; 1,2-Ethoxycarbonyl diazene solution; NSC 3474

DATABASE IDS

• MDL Number: MFCD00009103
• CAS Number: 1972-28-7
• PubChem SID: 24847277
• Beilstein Number: 908662

PROPERTIES

• Concentration: ~40% in toluene (H-NMR)
• Grade: purum
• Linear Formula: C2H5OCON=NCOOC2H5
• Flash Point: 41 °C
• Flash Point: 105.8 °F
• Refractive Index: n20/D 1.47
• GHS Signal Word: Danger
• GHS Hazard statements: H226-H304-H315-H319-H335-H336-H361d-H373
• European Hazard Symbols: Harmful (Xn)
• Personal Protective Equipment: Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
• GHS Precautionary statements: P261-P281-P301 + P310-P305 + P351 + P338-P331
• RID/ADR: UN 3379 3/PG 1
• Risk Statements: 63-10-20-36/37/38-48/20-65
• Safety Statements: 26-36/37-62
• Storage Temperature: 2-8°C
• Hazard Class: 3
• UN Number: 3379
• Packing Group: 1
• German water hazard class: 3

DETAILS

Description (English)

Other Notes
Reagent used in the Mitsunobu reaction, reviews9,10,11
Application
Reactant for preparation of:
• Immunostimulants α-Galactosylceramides1
• Cellotriose and cellotetraose analogues as transition state mimics for mechanistic studies of cellulases2
• Bisubstrate inhibitors with molecular recognition at the active site of catechol-O-methyltransferase3
• Derivatives of F200 and S383 with cannabinoid CB1 receptor binding activities4
• Aza-β-lactams via NHC-catalyzed [2 + 2] cycloaddition with ketenes5Reagent for:
• Annulation of N-protected imines6
• α-thiocyanation of enolizable ketones with ammonium thiocyanate7
• Diels-Alder reactions8

Description (简体中文)

Other Notes
用于 Mitsunobu 反应的试剂，综述9,10,11
Application
Reactant for preparation of:
• Immunostimulants α-Galactosylceramides1
• Cellotriose and cellotetraose analogues as transition state mimics for mechanistic studies of cellulases2
• Bisubstrate inhibitors with molecular recognition at the active site of catechol-O-methyltransferase3
• Derivatives of F200 and S383 with cannabinoid CB1 receptor binding activities4
• Aza-β-lactams via NHC-catalyzed [2 + 2] cycloaddition with ketenes5Reagent for:
• Annulation of N-protected imines6
• α-thiocyanation of enolizable ketones with ammonium thiocyanate7
• Diels-Alder reactions8