Sodium orthovanadate

• Catalog No.: 220590
• CAS Number: 13721-39-6
• M. F.: Na3O4V
• M. W.: 183.90841

SYNONYMS

• Title: 正钒酸钠
• IUPAC name: trisodium oxovanadiumtris(olate)
• IUPAC Traditional name: trisodium vanadate(3-)

DATABASE IDS

• CAS Number: 13721-39-6
• EC Number: 237-287-9
• MDL Number: MFCD00003511

PROPERTIES

• Linear Formula: Na3VO4
• Melting Point: 850-866 °C(lit.)
• GHS Signal Word: Warning
• GHS Hazard statements: H302 + H312 + H332
• European Hazard Symbols: Harmful (Xn)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Faceshields, Gloves
• GHS Precautionary statements: P280
• Risk Statements: 20/21/22
• RTECS: YW1120000
• Safety Statements: 22-36
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Inhibits ATPase, alkaline phosphatase and tyrosine phosphatase. Decavanadate, which is formed at acidic pH, inhibits inositol 1,4,5-trisphosphate (IP3)-induced Ca2+ release from endocrine cells and blocks IP3 binding to its receptor in brain tissue.
Application
Agent used in the study of diabetes.1

Description (简体中文)

Biochem/physiol Actions
抑制 ATP 酶、碱性磷酸酶和酪氨酸磷酸酶。在酸性 PH 值下形成的十钒酸盐可抑制肌醇基 1,4,5-三磷酸 (IP3)-诱导 Ca2+ 从内分泌细胞中的释放以及阻止 IP3 与其受体在脑组织中的结合。
Application
用于研究糖尿病的试剂。1