Ethyl dimethylphosphonoacetate

• Catalog No.: 365262
• CAS Number: 311-46-6
• M. F.: C6H13O5P
• M. W.: 196.138181
• Purity: 98%

SYNONYMS

• Title: 乙基膦酰基乙酸二甲酯
• IUPAC name: ethyl 2-(dimethoxyphosphoryl)acetate
• IUPAC Traditional name: ethyl 2-(dimethoxyphosphoryl)acetate
• Synonyms: 二甲基膦酰基乙酸乙酯; 乙氧基羰基甲基膦酸二甲酯; Ethoxycarbonylmethylphosphonic acid dimethylester; Phosphonoacetic acid P,P-dimethyl ethylester

DATABASE IDS

• CAS Number: 311-46-6
• EC Number: 206-222-6
• MDL Number: MFCD00015677
• Beilstein Number: 1777603

PROPERTIES

• Linear Formula: (CH3O)2P(O)CH2COOC2H5
• Purity: 98%
• Boiling Point: 134 °C/10 mmHg(lit.)
• Density: 1.188 g/mL at 25 °C(lit.)
• Flash Point: 99 °C
• Flash Point: 210.2 °F
• Refractive Index: n20/D 1.435(lit.)
• German water hazard class: 3

DETAILS

Description (English)

Application
Reactant for synthesis of:
• Non-nucleoside inhibitors of HCV polymerase NS5B1
• Neuropeptide Y1 receptor antagonists2
• Alkenylcarboxylates from Horner-Wadsworth-Emmons reactions3Reactant for:
• Enantioselective transfer hydrogenation for preparation of the C7-C14 fragment of ulapualide A4
• Intramolecular Michael reactions5
• Olefination of peptidyl aldehydes with stabilized ylides6

Description (简体中文)

Application
Reactant for synthesis of:
• Non-nucleoside inhibitors of HCV polymerase NS5B1
• Neuropeptide Y1 receptor antagonists2
• Alkenylcarboxylates from Horner-Wadsworth-Emmons reactions3Reactant for:
• Enantioselective transfer hydrogenation for preparation of the C7-C14 fragment of ulapualide A4
• Intramolecular Michael reactions5
• Olefination of peptidyl aldehydes with stabilized ylides6