Boron tribromide

• Catalog No.: 230367
• CAS Number: 10294-33-4
• M. F.: BBr3
• M. W.: 250.523
• Purity: ≥99.99%

SYNONYMS

• Title: 三溴化硼
• IUPAC name: tribromoborane
• IUPAC Traditional name: boron tribromide
• Synonyms: Tribromoboron

DATABASE IDS

• PubChem SID: 24853799
• EC Number: 233-657-9
• CAS Number: 10294-33-4
• MDL Number: MFCD00011312

PROPERTIES

• Empirical Formula (Hill Notation): BBr3
• Purity: ≥99.99%
• Boiling Point: ~90 °C(lit.)
• Density: 2.60 g/mL at 20 °C(lit.)
• Flash Point: 91 °C
• Flash Point: 195.8 °F
• Melting Point: -46 °C(lit.)
• Vapor Density: 8.6 (vs air)
• Vapor Pressure: 40 mmHg ( 14 °C)
• GHS Signal Word: Danger
• GHS Hazard statements: H300-H314-H330
• European Hazard Symbols: Highly toxic (T+)
• European Hazard Symbols: Corrosive (C)
• Personal Protective Equipment: Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
• GHS Precautionary statements: P260-P264-P280-P284-P305 + P351 + P338-P310
• RID/ADR: UN 2692 8/PG 1
• Risk Statements: 14-26/28-35
• RTECS: ED7400000
• Safety Statements: 9-26-28-36/37/39-45
• Supplemental Hazard Statements: Reacts violently with water.
• Hazard Class: 8
• UN Number: 2692
• Packing Group: 1
• German water hazard class: 3

DETAILS

Description (English)

Packaging
5, 25, 100 g in ampule
Application
Reactant for preparation of:
• Drug intermediate 6-nitro-L-DOPA1
• Luminescent polystyrene derivatives with sterically protected carbazolylborane moieties2
• High-quality boron-doped graphene via Wurtz-type reductive coupling reaction3
• Mercapto-(+)-methamphetamine haptens for synthesis of (+)-methamphetamine conjugate vaccines with improved epitope densities4
• Micrometer-sized organic molecule-DNA hybrid structures5
• Borane complexes via electrophilic aromatic borylation reactions6
• A 5-HT2C receptor agonist7
• Biphenyl-derivatives possessing tertiary amino groups as β-secretase(BACE1) inhibitors for the treatment of Alzheimer′s disease8
• A highly near-IR region fluorescent p-extended boron aza-dipyrromethene moiety unit9
• Tetrahydroisoquinoline derivatives via intramolecular cyclization of methoxy-substituted N-phenethylimides10
With alkynes forms 2-alkenyldibromoboranes, which show reversed regiochemistry in Diels-Alder reactions as compared to BBN. Intermediates generated from 1-alkynes couple to alkyl halides providing trisubstituted alkenes. Reacts with chiral sulfonamides to provide precursors of chiral glycidol esters, acetate diols, β-hydroxy esters, and amino acid esters. Useful for the synthesis of precursors to group 13-15 semiconductor materials.

Description (简体中文)

包装
5, 25, 100 g in ampule
Application
Reactant for preparation of:
• Drug intermediate 6-nitro-L-DOPA1
• Luminescent polystyrene derivatives with sterically protected carbazolylborane moieties2
• High-quality boron-doped graphene via Wurtz-type reductive coupling reaction3
• Mercapto-(+)-methamphetamine haptens for synthesis of (+)-methamphetamine conjugate vaccines with improved epitope densities4
• Micrometer-sized organic molecule-DNA hybrid structures5
• Borane complexes via electrophilic aromatic borylation reactions6
• A 5-HT2C receptor agonist7
• Biphenyl-derivatives possessing tertiary amino groups as β-secretase(BACE1) inhibitors for the treatment of Alzheimer′s disease8
• A highly near-IR region fluorescent p-extended boron aza-dipyrromethene moiety unit9
• Tetrahydroisoquinoline derivatives via intramolecular cyclization of methoxy-substituted N-phenethylimides10
与炔烃反应生成 2-烯基二溴硼烷，在 Diels-Alder 反应中与 BBN 相比表现出反向区域选择性。由 1-炔烃与提供三取代烯烃的卤代烷发生偶联反应生成的中间体。与手性磺酰胺反应生成手性缩水甘油酯、二醇乙酸酯、β-羟基酯和氨基酸酯的前体。可用于 13-15 族半导体材料前体的合成。