6-Aminocaproic acid

• Catalog No.: A44606
• CAS Number: 60-32-2
• M. F.: C6H13NO2
• M. W.: 131.17292
• Purity: 98%

SYNONYMS

• Title: 6-氨基己酸
• IUPAC name: 6-aminohexanoic acid
• IUPAC Traditional name: aminocaproic acid
• Synonyms: EACA; 6-氨己酸; ε-Aminocaproic acid; 6-aminohexanoic acid; ε-氨基己酸

DATABASE IDS

• EC Number: 200-469-3
• MDL Number: MFCD00008238
• Beilstein Number: 906872
• CAS Number: 60-32-2

PROPERTIES

• Linear Formula: H2N(CH2)5CO2H
• Purity: 98%
• Gene Information: human ... PLG(5340)
• Melting Point: 207-209 °C (dec.)(lit.)
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P261-P305 + P351 + P338
• Risk Statements: 36/37/38
• RTECS: MO6300000
• Safety Statements: 26-36
• German water hazard class: 2

DETAILS

Description (English)

Application
Hemostat.2,6 Used as a lysine analogue to characterize binding sites in plasminogen.7,8
Biochem/physiol Actions
Lysine analog. Promotes rapid dissociation of plasmin, thereby inhibiting the activation of plasminogen and subsequent fibrinolysis.1,2 Reported to inhibit plasminogen binding to activated platelets.3 An early report indicated that it inhibits the activation of the first component of the complement system.4 Binds and inactivates Carboxypeptidase B.5

Description (简体中文)

Application
止血剂。2,6用作赖氨酸类似物，用于表征纤溶酶原中的结合位点。7,8
Biochem/physiol Actions
赖氨酸类似物。促进纤溶酶快速解离，从而抑制纤溶酶原的活化以及后续的纤维蛋白溶解。1,2据报告，EACA 可抑制纤溶酶原结合至活化的血小板。3早期报告表明，EACA 可抑制补体系统第一组分的活化。4结合并灭活羧肽酶 B。5