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6-Aminocaproic acid

Catalog No. A44606 Name Sigma Aldrich
CAS Number 60-32-2 Website http://www.sigmaaldrich.com
M. F. C6H13NO2 Telephone 1-800-521-8956
M. W. 131.17292 Fax
Purity 98% Email
Storage Chembase ID: 395

SYNONYMS

Title
6-氨基己酸
IUPAC name
6-aminohexanoic acid
IUPAC Traditional name
aminocaproic acid
Synonyms
EACA
6-氨己酸
ε-Aminocaproic acid
6-aminohexanoic acid
ε-氨基己酸

DATABASE IDS

EC Number 200-469-3
MDL Number MFCD00008238
Beilstein Number 906872
CAS Number 60-32-2

PROPERTIES

Linear Formula H2N(CH2)5CO2H
Purity 98%
Gene Information human ... PLG(5340)
Melting Point 207-209 °C (dec.)(lit.)
GHS Pictograms GHS07
GHS Signal Word Warning
GHS Hazard statements H315-H319-H335
European Hazard Symbols Irritant Irritant (Xi)
MSDS Link Download
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
GHS Precautionary statements P261-P305 + P351 + P338
Risk Statements 36/37/38
RTECS MO6300000
Safety Statements 26-36
German water hazard class 2

DETAILS

Description (English)
Application
Hemostat.2,6 Used as a lysine analogue to characterize binding sites in plasminogen.7,8
Biochem/physiol Actions
Lysine analog. Promotes rapid dissociation of plasmin, thereby inhibiting the activation of plasminogen and subsequent fibrinolysis.1,2 Reported to inhibit plasminogen binding to activated platelets.3 An early report indicated that it inhibits the activation of the first component of the complement system.4 Binds and inactivates Carboxypeptidase B.5
Description (简体中文)
Application
止血剂。2,6用作赖氨酸类似物,用于表征纤溶酶原中的结合位点。7,8
Biochem/physiol Actions
赖氨酸类似物。促进纤溶酶快速解离,从而抑制纤溶酶原的活化以及后续的纤维蛋白溶解。1,2据报告,EACA 可抑制纤溶酶原结合至活化的血小板。3早期报告表明,EACA 可抑制补体系统第一组分的活化。4结合并灭活羧肽酶 B。5

REFERENCES