D-Amygdalin

• Catalog No.: A83202
• CAS Number: 29883-15-6
• M. F.: C20H27NO11
• M. W.: 457.42848

SYNONYMS

• Title: D-苦杏苷
• IUPAC name: 2-phenyl-2-{[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-({[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)oxan-2-yl]oxy}acetonitrile
• IUPAC Traditional name: amygdalin
• Synonyms: D-Mandelonitrile 6-O-β-D-glucosido-β-D-glucoside; Laetrile; D-Mandelonitrile-β-gentiobioside; D-扁桃腈6-O-β-D-葡糖基-β-D-葡萄糖苷; D-Mandelonitrile β-gentiobioside; Amygdalin; D-扁桃腈-β-龙胆二糖苷; D-杏仁腈β-龙胆二糖苷; 扁桃苷; 苦杏仁苷

DATABASE IDS

• MDL Number: MFCD00006598
• Beilstein Number: 66856
• EC Number: 249-925-3
• CAS Number: 29883-15-6

PROPERTIES

• Empirical Formula (Hill Notation): C20H27NO11
• Melting Point: 223-226 °C(lit.)
• Optical Rotation: [α]22/D -38°, c = 1.2 in H2O
• GHS Signal Word: Warning
• GHS Hazard statements: H302
• European Hazard Symbols: Harmful (Xn)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Faceshields, Gloves
• Risk Statements: 22
• RTECS: OO8450000
• Safety Statements: 26-36/37/39-45
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Cyanogenic glycoside that is a component of bitter almonds and apricot pits. There is no scientific evidence that amygdalin itself is an effective anti-cancer agent. Recent studies using β-glucoside linked to a tumor-associated monoclonal antibody to release cyanide at the tumor cell has shown significant cytotoxicity.

Description (简体中文)

Biochem/physiol Actions
生氰糖苷是苦杏仁与杏核的成分之一。尚无科学证明显示苦杏苷是一种有效的抗癌剂。最近的研究将 β-葡萄糖苷结合到肿瘤相关单克隆抗体，以针对肿瘤细胞释放氰化物，结果表现出显著的细胞毒性。