[2S-(2α,3β,8aβ)]-(+)-Hexahydro-3-(hydroxymethyl)-8a-methyl-2-phenyl-5H-oxazolo[3,2-a]pyridin-5-one

• Catalog No.: 388114
• CAS Number: 116950-01-7
• M. F.: C15H19NO3
• M. W.: 261.31626
• Purity: 98%

SYNONYMS

• Title: [2S-(2α,3β,8aβ)]-(+)-六氢-3-(羟甲基)-8a-甲基-2-苯基-5H-噁唑并[3,2-a]吡啶-5-酮
• IUPAC name: (2R,3R,8aS)-3-(hydroxymethyl)-8a-methyl-2-phenyl-hexahydro-2H-[1,3]oxazolo[3,2-a]pyridin-5-one
• IUPAC Traditional name: (2R,3R,8aS)-3-(hydroxymethyl)-8a-methyl-2-phenyl-tetrahydro-2H-[1,3]oxazolo[3,2-a]pyridin-5-one

DATABASE IDS

• PubChem SID: 24864208
• CAS Number: 116950-01-7
• MDL Number: MFCD00192204

PROPERTIES

• Empirical Formula (Hill Notation): C15H19NO3
• Purity: 98%
• Melting Point: 96-100 °C(lit.)
• Optical Rotation: [α]23/D +14°, c = 1 in ethanol
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P261-P305 + P351 + P338
• Risk Statements: 36/37/38
• Safety Statements: 26-36
• German water hazard class: 3

DETAILS

Description (English)

Application
Chiral bicyclic lactams such as this are useful templates for asymmetric synthesis.1 High levels of asymmetric induction have been obtained in cycloadditions,2,3 alkylations,4,5,6 conjugate additions,7,8 annulations,9 and dihydroxylations.10
Packaging
5 g in glass bottle

Description (简体中文)

Application
诸如此类的手性双环内酰胺是用于不对称合成的有用模板。1已在以下反应中实现了高水平的不对称诱导：环加成、2,3烷基化、4,5,6共轭加成、7,8成环、9以及双羟基化。10
包装
5 g in glass bottle