(3R-cis)-(-)-2,3-Dihydro-7a-methyl-3-phenylpyrrolo[2,1-b]oxazol-5(7aH)-one

• Catalog No.: 458562
• CAS Number: 302911-95-1
• M. F.: C13H13NO2
• M. W.: 215.24782
• Purity: 98%

SYNONYMS

• Title: (3R-顺)-(-)-2,3-二氢-7a-甲基-3-苯基吡咯并[2,1-b]噁唑-5(7aH)-酮
• IUPAC name: (3R,7aS)-7a-methyl-3-phenyl-2H,3H,5H,7aH-pyrrolo[2,1-b][1,3]oxazol-5-one
• IUPAC Traditional name: (3R,7aS)-7a-methyl-3-phenyl-2H,3H-pyrrolo[2,1-b][1,3]oxazol-5-one

DATABASE IDS

• MDL Number: MFCD00274330
• PubChem SID: 24869480
• CAS Number: 302911-95-1

PROPERTIES

• Empirical Formula (Hill Notation): C13H13NO2
• Optical Purity: ee: ≥99% (HPLC)
• Purity: 98%
• Melting Point: 90-92 °C(lit.)
• Optical Rotation: [α]20/D -124°, c = 1 in chloroform
• GHS Signal Word: Warning
• GHS Hazard statements: H302-H312-H332
• European Hazard Symbols: Harmful (Xn)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P280
• Risk Statements: 20/21/22
• Safety Statements: 36
• German water hazard class: 3

DETAILS

Description (English)

Application
High levels of asymmetric induction1 have been obtained with this chiral bicyclic lactam in cycloadditions,2,3 alkylations,4,5,6 conjugate additions,7,8 annulations,9 and dihydroxylations.10

Description (简体中文)

Application
1已通过该手性双环内酰胺在以下反应中实现了高水平的不对称诱导：环加成、2,3烷基化、4,5,6共轭加成、7,8成环9以及双羟基化。10