Acetylsalicylic acid

• Catalog No.: 132926
• CAS Number: 50-78-2
• M. F.: C9H8O4
• M. W.: 180.15742
• Purity: 99%

SYNONYMS

• Title: 乙酰水杨酸
• IUPAC name: 2-(acetyloxy)benzoic acid
• IUPAC Traditional name: aspirin
• Synonyms: O-Acetylsalicylic acid; 2-乙酰氧基苯甲酸; Aspirin; ASA; 2-Acetoxybenzoic acid; O-乙酰基水杨酸; 阿斯匹林

DATABASE IDS

• Beilstein Number: 779271
• MDL Number: MFCD00002430
• EC Number: 200-064-1
• CAS Number: 50-78-2

PROPERTIES

• Linear Formula: 2-(CH3CO2)C6H4CO2H
• Purity: 99%
• Flash Point: 250 °C
• Flash Point: 482 °F
• Melting Point: 134-136 °C(lit.)
• GHS Signal Word: Warning
• GHS Hazard statements: H302-H315-H319-H335
• European Hazard Symbols: Harmful (Xn)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Faceshields, Gloves
• GHS Precautionary statements: P261-P305 + P351 + P338
• Risk Statements: 22-36/37/38
• RTECS: VO0700000
• Safety Statements: 26
• German water hazard class: 1

DETAILS

Description (English)

Biochem/physiol Actions
Blocks the production of prostaglandins by inhibiting cyclooxygenase (prostaglandin H synthase), with greater selectivity toward the COX-1 isoform. The antithrombotic effect is due to the inhibition of COX-1 in platelets that blocks thromboxane production and platelet aggregation. Chemopreventive against colorectal and other solid tumors.

Description (简体中文)

Biochem/physiol Actions
通过抑制环加氧酶（前列腺素 H 合成酶）来阻断前列腺素的生成，对 COX-1 亚型具有较高的选择性。可抑制血小板中的 COX-1，从而阻断血栓素的生成和血小板凝集，因此具有抗血栓形成的作用。针对结直肠和其他实体瘤的化学防治剂。