Amitriptyline hydrochloride

• Catalog No.: 284629
• CAS Number: 549-18-8
• M. F.: C20H24ClN
• M. W.: 313.86426
• Purity: 99%

SYNONYMS

• Title: 阿米替林 盐酸盐
• IUPAC name: dimethyl(3-{tricyclo[9.4.0.0^3,^8]pentadeca-1(11),3,5,7,12,14-hexaen-2-ylidene}propyl)amine hydrochloride
• IUPAC Traditional name: dimethyl(3-{tricyclo[9.4.0.0^3,^8]pentadeca-1(11),3,5,7,12,14-hexaen-2-ylidene}propyl)amine hydrochloride

DATABASE IDS

• EC Number: 208-964-6
• MDL Number: MFCD00012537
• CAS Number: 549-18-8

PROPERTIES

• Empirical Formula (Hill Notation): C20H23N · HCl
• Purity: 99%
• GHS Signal Word: Danger
• GHS Hazard statements: H301-H361
• European Hazard Symbols: Harmful (Xn)
• Personal Protective Equipment: Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
• GHS Precautionary statements: P281-P301 + P310
• RID/ADR: UN 2811 6.1/PG 3
• Risk Statements: 63-22
• RTECS: HO9450000
• Safety Statements: 22
• Hazard Class: 6.1
• UN Number: 2811
• Packing Group: 3
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Tricyclic antidepressant; inhibits the norepinephrine and serotonin transporters with Kis of 100 nM and 14.7 nM, respectively; high in vitro affinity for α1-adrenoceptors, serotonin and muscarinic acetylcholine receptors.

Description (简体中文)

Biochem/physiol Actions
三环抗抑郁剂；抑制分别具有 100nM 和 14.7nM Kis 的去甲肾上腺素和 5-羟色胺转运蛋白；对 α1-肾上腺素受体、5-羟色胺和毒蕈碱型乙酰胆碱受体具有高度的体外亲和力。