Harmaline

• Catalog No.: 286036
• CAS Number: 304-21-2
• M. F.: C13H14N2O
• M. W.: 214.26306
• Purity: 97%

SYNONYMS

• Title: 骆驼蓬灵
• IUPAC name: 7-methoxy-1-methyl-3H,4H,9H-pyrido[3,4-b]indole
• IUPAC Traditional name: harmaline
• Synonyms: Dihydroharmine; 4,9-Dihydro-7-methoxy-1-methyl-3H-pyrido[3,4-b]indole; 7-甲氧基-1-甲基-4,9-二氢-3H-吡啶并[3,4-b]吲哚; 1-Methyl-7-methoxy-3,4-dihydro-β-carboline; Harmalol methyl ether; NSC 407285; Harmidine; 1-甲基-7-甲氧基-3,4-二氢-β-咔啉; 3,4-二氢骆驼蓬碱; O-甲基骆驼蓬酚

DATABASE IDS

• Beilstein Number: 207310
• CAS Number: 304-21-2
• MDL Number: MFCD00004955
• EC Number: 206-152-6

PROPERTIES

• Empirical Formula (Hill Notation): C13H14N2O
• Purity: 97%
• Melting Point: 232-234 °C(lit.)
• Drug Control: regulated under CDSA - not available from Sigma-Aldrich Canada
• Drug Control: stupéfiantregulated under CDSA - not available from Sigma-Aldrich Canada
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• RTECS: UU9800000
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
CNS stimulant; may act through NMDA receptors
Application
Reactant for preparation of:
• Acylated harmalines via Friedel-Crafts reaction1
• Phenacyl derivatives of 1-methyl-7-methoxy-β-carbolines as central nervous system affectors2
• Palladium harmaline DMSO chloro complex as anti-tumor agent3Natural product scaffold in preparation of:
• Trypanothione reductase inhibitors†

Description (简体中文)

Biochem/physiol Actions
中枢神经系统兴奋剂；可通过 NMDA 受体起作用
Application
Reactant for preparation of:
• Acylated harmalines via Friedel-Crafts reaction1
• Phenacyl derivatives of 1-methyl-7-methoxy-β-carbolines as central nervous system affectors2
• Palladium harmaline DMSO chloro complex as anti-tumor agent3Natural product scaffold in preparation of:
• Trypanothione reductase inhibitors†