Diethyl azodicarboxylate solution

• Catalog No.: 563110
• CAS Number: 1972-28-7
• M. F.: C6H10N2O4
• M. W.: 174.1546

SYNONYMS

• Title: 偶氮二甲酸二乙酯 溶液
• IUPAC name: N-[(ethoxycarbonyl)imino]ethoxyformamide
• IUPAC Traditional name: diethyl azodicarboxylate
• Synonyms: Unifoam AZ-AE 200; Diethoxycarbonyldiazene solution; NSC 679015; Diethyl azodiformate solution; DEAD; 1,2-Ethoxycarbonyl diazene solution; NSC 3474

DATABASE IDS

• MDL Number: MFCD00009103
• CAS Number: 1972-28-7
• Beilstein Number: 908662
• PubChem SID: 24880080

PROPERTIES

• Concentration: 40 wt. % in toluene
• Linear Formula: C2H5OCON=NCOOC2H5
• Boiling Point: 116-117 °C
• Density: 0.956 g/mL at 25 °C
• Flash Point: 41 °C
• Flash Point: 105.8 °F
• Refractive Index: n20/D 1.4690
• GHS Signal Word: Danger
• GHS Hazard statements: H226-H242-H304-H315-H319-H335 + H336-H361d-H373
• European Hazard Symbols: Harmful (Xn)
• Personal Protective Equipment: Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
• GHS Precautionary statements: P261-P281-P301 + P310-P305 + P351 + P338-P331
• RID/ADR: UN 3379 3/PG 1
• Risk Statements: 63-5-10-20-36/37/38-48/20-65
• Safety Statements: 26-36/37-62
• Storage Temperature: 2-8°C
• Hazard Class: 3
• UN Number: 3379
• Packing Group: 1
• German water hazard class: 3

DETAILS

Description (简体中文)

Application
常用于 Mitsunobo 反应的活化试剂。9
Reactant for preparation of:
• Immunostimulants α-Galactosylceramides1
• Cellotriose and cellotetraose analogues as transition state mimics for mechanistic studies of cellulases2
• Bisubstrate inhibitors with molecular recognition at the active site of catechol-O-methyltransferase3
• Derivatives of F200 and S383 with cannabinoid CB1 receptor binding activities4
• Aza-β-lactams via NHC-catalyzed [2 + 2] cycloaddition with ketenes5Reagent for:
• Annulation of N-protected imines6
• α-thiocyanation of enolizable ketones with ammonium thiocyanate7
• Diels-Alder reactions8
General description
DOT Special Approval Submission is Under Review. Availability is Estimated as March 2012.
包装
25, 100 g in glass bottle
每 100g 约含 40g DEAD 溶质
每 25g 约含 10g DEAD 溶质
Warning
有毒性、刺激性、易燃

Description (English)

Application
A commonly used activating reagent in Mitsunobo reactions.9
Reactant for preparation of:
• Immunostimulants α-Galactosylceramides1
• Cellotriose and cellotetraose analogues as transition state mimics for mechanistic studies of cellulases2
• Bisubstrate inhibitors with molecular recognition at the active site of catechol-O-methyltransferase3
• Derivatives of F200 and S383 with cannabinoid CB1 receptor binding activities4
• Aza-β-lactams via NHC-catalyzed [2 + 2] cycloaddition with ketenes5Reagent for:
• Annulation of N-protected imines6
• α-thiocyanation of enolizable ketones with ammonium thiocyanate7
• Diels-Alder reactions8
General description
DOT Special Approval Submission is Under Review. Availability is Estimated as March 2012.
Packaging
100g unit contains ca. 40g DEAD solute
25g unit contains ca. 10g DEAD solute
25, 100 g in glass bottle
Warning
Toxic, Irritant, Flammable