Adenosine

• Catalog No.: 146595
• CAS Number: 58-61-7
• M. F.: C10H13N5O4
• M. W.: 267.24132
• Purity: ≥99%

SYNONYMS

• Title: 腺苷
• IUPAC name: (2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
• IUPAC Traditional name: adenosine
• Synonyms: 9-β-D-Ribofuranosyladenine; Adenine-9-β-D-ribofuranoside; Adenine Riboside; 9-β-D-呋喃核糖基腺嘌呤; 腺嘌呤-9-β-D-呋喃核糖苷; 腺嘌呤核苷

DATABASE IDS

• CAS Number: 58-61-7
• MDL Number: MFCD00005752
• EC Number: 200-389-9
• Beilstein Number: 93029

PROPERTIES

• Empirical Formula (Hill Notation): C10H13N5O4
• Purity: ≥99%
• Melting Point: 234-236 °C(lit.)
• Optical Rotation: [α]22/D -60.2°, c = 0.7 in H2O
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• German water hazard class: 2

DETAILS

Description (English)

Biochem/physiol Actions
Endogenous neurotransmitter at adenosine receptors. Cardioprotective effects may relate to activation of A1 adenosine receptors. The antiplatelet and anti-inflammatory actions of adenosine appear to be mediated via the A2 adenosine receptor. In contrast, adenosine appears to be a pro-inflammatory mediator in asthma and chronic obstructive pulmonary disease (COPD).

Description (简体中文)

Biochem/physiol Actions
腺苷受体处的内源性神经递质。心肌保护作用可能与 A1 腺苷受体的激活有关。通过 A2 腺苷受体可介导腺苷的抗血小板和抗炎作用。相比之下，腺苷在哮喘和慢性阻塞性肺部疾病 (COPD) 中起促炎介质作用。