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Secobarbital

Catalog No. DB00418 Name DrugBank
CAS Number 76-73-3 Website http://www.ualberta.ca/
M. F. C12H18N2O3 Telephone (780) 492-3111
M. W. 238.28292 Fax (780) 492-1071
Purity Email david.wishart@ualberta.ca
Storage Chembase ID: 301

SYNONYMS

IUPAC name
5-[(2R)-pentan-2-yl]-5-(prop-2-en-1-yl)-1,3-diazinane-2,4,6-trione
IUPAC Traditional name
pramil
Brand Name
Secobarbitone
Imesonal
Evrronal
Somosal
Meballymal sodium
Bipanal
Bipinal sodium
Meballymal
Novosecobarb
Quinalspan
Seco 8
Synate
Barbosec
Evronal
Evronal Sodium
Hypotrol
Hyptran
Immenoctal
Immenox
Meballymalum
Pramil
Quinalbarbital
Quinalbarbitone
Quinalbarbitone sodium
Sebar
Seconal
Sedutain
Seotal
Trisomnin
Synonyms
(+/-)-Secobarbital
Secobarbital Sodium
Sodium Secobarbital
Secobarbitale [DCIT]
Secobarbitalum [INN-Latin]
Sodium quinalbarbitone

DATABASE IDS

CAS Number 76-73-3

PROPERTIES

Hydrophobicity(logP) 2.3
Solubility 550 mg/L

DETAILS

Description (English)
Item Information
Drug Groups approved
Description Secobarbital (marketed by Eli Lilly and Company under the brand names Seconal? and Tuinal) is a barbiturate derivative drug. It possesses anaesthetic, anticonvulsant, sedative and hypnotic properties. In the United Kingdom, it was known as Quinalbarbitone.
Indication For the Short-term treatment of intractable insomnia for patients habituated to barbiturates
Pharmacology Secobarbital, a barbiturate, is used for the induction of anesthesia prior to the use of other general anesthetic agents and for induction of anesthesia for short surgical, diagnostic, or therapeutic procedures associated with minimal painful stimuli. Little analgesia is conferred by barbiturates; their use in the presence of pain may result in excitation.
Toxicity Symptoms of an overdose typically include sluggishness, incoordination, difficulty in thinking, slowness of speech, faulty judgment, drowsiness or coma, shallow breathing, staggering, and in severe cases coma and death.
Affected Organisms
Humans and other mammals
Elimination Barbiturates are metabolized primarily by the hepatic microsomal enzyme system, and the metabolic products are excreted in the urine and, less commonly, in the feces.
External Links
Wikipedia
Drugs.com

REFERENCES