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Carbimazole

Catalog No. DB00389 Name DrugBank
CAS Number 22232-54-8 Website http://www.ualberta.ca/
M. F. C7H10N2O2S Telephone (780) 492-3111
M. W. 186.2315 Fax (780) 492-1071
Purity Email david.wishart@ualberta.ca
Storage Chembase ID: 272

SYNONYMS

IUPAC name
ethyl 3-methyl-2-sulfanylidene-2,3-dihydro-1H-imidazole-1-carboxylate
IUPAC Traditional name
carbimazole
Brand Name
Atirozidina
Carbimazol Spofa
CG1
Neo-Thyreostat
Basolest
Carbotiroid
Mertiran
Neo-Mercazole
Neo-Tireol
Neomercazole
Tyrazol
Synonyms
Athyromazole
Carbethoxymethimazole
Carbimazolum [INN-Latin]
Carbinazole
Carbimazol
Carbimazol [INN-Spanish, French]

DATABASE IDS

PubChem SID 46506359
PubChem CID 31072
CAS Number 22232-54-8

PROPERTIES

Hydrophobicity(logP) 0.4

DETAILS

Description (English)
Item Information
Drug Groups approved
Description An imidazole antithyroid agent. Carbimazole is metabolized to methimazole, which is responsible for the antithyroid activity. [PubChem]
Indication For the treatment of hyperthyroidism and thyrotoxicosis. It is also used to prepare patients for thyroidectomy.
Pharmacology Carbimazole is a carbethoxy derivative of methimazole. Its antithyroid action is due to its conversion to methimazole after absorption. It is used to treat hyperthyroidism and thyrotoxicosis.
Affected Organisms
Humans and other mammals
Protein Binding 85%
External Links
Wikipedia

REFERENCES