| Item |
Information |
|
Drug Groups
|
approved |
|
Description
|
An anticonvulsant effective in absence seizures, but generally reserved for refractory cases because of its toxicity. (From AMA Drug Evaluations Annual, 1994, p378) |
| Indication |
Used in the control of absence (petit mal) seizures that are refractory to treatment with other medications. |
| Pharmacology |
Paramethadione and trimethadione are anticonvulsants indicated in the control of absence (petit mal) seizures that are refractory to treatment with other medications. Dione anticonvulsants are used in the treatment of epilepsy. They act on the central nervous system (CNS) to reduce the number of seizures. |
| Toxicity |
Symptoms of overdose include clumsiness or unsteadiness, coma, dizziness (severe), drowsiness (severe), nausea (severe), and problems with vision. |
| Affected Organisms |
| • |
Humans and other mammals |
|
| Protein Binding |
90% |
| External Links |
|
|