4-Bromo-calcium Ionophore A23187

• Catalog No.: B7272
• CAS Number: 76455-48-6
• M. F.: C29H36BrN3O6
• M. W.: 602.51664

SYNONYMS

• IUPAC name: 6-bromo-5-(methylamino)-2-{[(2R,3R,6S,8S,9R,11R)-3,9,11-trimethyl-8-[(2S)-1-oxo-1-(1H-pyrrol-2-yl)propan-2-yl]-1,7-dioxaspiro[5.5]undecan-2-yl]methyl}-1,3-benzoxazole-4-carboxylic acid
• IUPAC Traditional name: 6-bromo-5-(methylamino)-2-{[(2R,3R,6S,8S,9R,11R)-3,9,11-trimethyl-8-[(2S)-1-oxo-1-(1H-pyrrol-2-yl)propan-2-yl]-1,7-dioxaspiro[5.5]undecan-2-yl]methyl}-1,3-benzoxazole-4-carboxylic acid
• Synonyms: 4-Bromo-A23187; 4-Bromo-calcimycin

DATABASE IDS

• PubChem SID: 24891982
• MDL Number: MFCD00077667
• CAS Number: 76455-48-6

PROPERTIES

• Apperance: yellow powder
• Solubility: ethanol: soluble20 mg/mL
• Solubility: DMSO: soluble
• GHS Signal Word: Warning
• GHS Hazard statements: H302-H312-H315-H319-H332-H335
• European Hazard Symbols: Harmful (Xn)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P261-P280-P305 + P351 + P338
• Risk Statements: 20/21/22-36/37/38
• Safety Statements: 26-36/37
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Application
Nonfluorescent Ca2+ ionophore that can be used to calibrate the quantitation of cytoplasmic free Ca2+ with fluorescent probes.
Biochem/physiol Actions
Ca2+ ionophore that is used to potentiate responses to NMDA, but not quisqualate.
Other Notes
Analog of calcium ionophore A23187