5-Chloro-2′-deoxyuridine

• Catalog No.: C6891
• CAS Number: 50-90-8
• M. F.: C9H11ClN2O5
• M. W.: 262.64704

SYNONYMS

• IUPAC name: 5-chloro-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione
• IUPAC Traditional name: 5-chloro-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-pyrimidine-2,4-dione
• Synonyms: CldU

DATABASE IDS

• PubChem SID: 24892910
• MDL Number: MFCD00006531
• CAS Number: 50-90-8

PROPERTIES

• GHS Signal Word: Warning
• GHS Hazard statements: H302-H312-H332-H351
• European Hazard Symbols: Harmful (Xn)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P280
• Risk Statements: 20/21/22-40
• RTECS: YU7400000
• Safety Statements: 36/37/39-45
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Application
5-Chloro-2′-deoxyuridine (CldU) is used as a thymidine analogue to study the miscoding potential of hypochlorous acid damage to DNA and DNA precursors. When used with antibody based immunofluorescent imaging, 5-Chloro-2′-deoxyuridine incorporation may be used in protocols to identify sites of DNA replication. CldU may be used as a labeling substrate in conjunction with other halogenated uridine labeling substrates such as bromodeoxyuridine (BrdU) and/or iododeoxyuridine (IdU).