Amsacrine hydrochloride

• Catalog No.: A9809
• CAS Number: 54301-15-4
• M. F.: C21H20ClN3O3S
• M. W.: 429.9198
• Purity: ≥98% (TLC)

SYNONYMS

• IUPAC name: N-{4-[(acridin-9-yl)amino]-3-methoxyphenyl}methanesulfonamide hydrochloride
• IUPAC Traditional name: amsacrine hydrochloride
• Synonyms: m-AMSA; 4-(9-Acridinylamino)-N-(methanesulfonyl)-m-anisidine hydrochloride

DATABASE IDS

• PubChem SID: 24278248
• MDL Number: MFCD07799963
• CAS Number: 54301-15-4

PROPERTIES

• Purity: ≥98% (TLC)
• Gene Information: human ... TOP2A(7153), TOP2B(7155)
• Apperance: red to brown powder
• Melting Point: 197-199 °C(lit.)
• Solubility: DMSO: soluble10 mg/mL (with heat and sonication)
• Solubility: 30% ethanol: soluble4 mg/mL
• GHS Signal Word: Danger
• GHS Hazard statements: H301-H315-H319-H335
• European Hazard Symbols: Toxic (T)
• Personal Protective Equipment: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
• GHS Precautionary statements: P261-P301 + P310-P305 + P351 + P338
• RID/ADR: UN 2811 6.1/PG 3
• Risk Statements: 25-36/37/38
• RTECS: PB1081000
• Safety Statements: 26-45
• Hazard Class: 6.1
• UN Number: 2811
• Packing Group: 3
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Amsacrine hydrochloride is a DNA topoisomerase II inhibitor.