Pyrantel pamoate

• Catalog No.: P6210
• CAS Number: 22204-24-6
• M. F.: C34H30N2O6S
• M. W.: 594.6768

SYNONYMS

• Title: 双羟萘酸噻嘧啶
• IUPAC name: 1-methyl-2-[(E)-2-(thiophen-2-yl)ethenyl]-1,4,5,6-tetrahydropyrimidine; 4-[(3-carboxy-2-hydroxynaphthalen-1-yl)methyl]-3-hydroxynaphthalene-2-carboxylic acid
• IUPAC Traditional name: pamoic acid; pyrantel
• Synonyms: Pyrantel embonate; 含 4,4′-亚甲基双(3-羟基-2-萘甲酸) 的 1-甲基-2-(2-[2-噻吩基]乙烯基)-1,4,5,6-四氢嘧啶化合物

DATABASE IDS

• Beilstein Number: 9034755
• MDL Number: MFCD00072037
• CAS Number: 22204-24-6
• EC Number: 244-837-1
• PubChem SID: 24898655

PROPERTIES

• Cation Traces: Zn: <0.0005%
• Ignition Residue: <0.5%
• Impurities: <0.0005% Phosphorus (P)
• Impurities: <0.1% Insoluble matter
• Antion Traces: chloride (Cl-): <0.5%
• Cation Traces: Al: <0.0005%
• Cation Traces: Ca: <0.002%
• Cation Traces: Cu: <0.0005%
• Cation Traces: Fe: <0.001%
• Cation Traces: K: <0.005%
• Cation Traces: Mg: <0.0005%
• Cation Traces: Na: <0.01%
• Cation Traces: Pb: <0.001%
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• German water hazard class: 3

DETAILS

Description (English)

Application
Pyrantel pamoate is used as a deworming agent in domesticated animals such as horses, hamsters, sheep, pigs, cats, and dogs1. It is a combination of pyrantel and pamoic acid. It is used to study mechanisms underlying gut dysfunction in a murine model2. It has been used as an anthelmintic treatment of children in Bangladesh and has been studied for it′s effect on host physiology, growth, and biochemical status3.
Biochem/physiol Actions
Pyrantel pamoate is a nematode muscle cell-associated nicotinic agonist for the acetylcholine (ACh) receptor. Cholinesterase inhibitor.