Rhodamine 123

• Catalog No.: R8004
• CAS Number: 62669-70-9
• M. F.: C21H17ClN2O3
• M. W.: 380.82428

SYNONYMS

• IUPAC name: methyl 2-(6-amino-3-imino-3H-xanthen-9-yl)benzoate hydrochloride
• IUPAC Traditional name: methyl 2-(3-amino-6-iminoxanthen-9-yl)benzoate hydrochloride
• Synonyms: 2-(6-Amino-3-imino-3H-xanthen-9-yl)benzoic acid methyl ester

DATABASE IDS

• PubChem SID: 24899403
• Beilstein Number: 6030951
• EC Number: 263-687-8
• MDL Number: MFCD00012664
• CAS Number: 62669-70-9

PROPERTIES

• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• RTECS: ZE0883000
• German water hazard class: 3

DETAILS

Description (简体中文)

Frequently Asked Questions
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Application
Useful as a laser dye and to have selective cell growth effects. Mitochondrial specific fluorescent dye and substrate for P-glycoprotein.
Biochem/physiol Actions
Fluorescent dye most commonly used in flow cytometry as functional reporter for Pgp. Functional assays for MDR proteins are better prognostic indicators in cancer therapy than levels of MDR protein expression. Rh 123 can be used in multiparameter analyses without fluorescence interference in combination with common protein labeling dyes such as PE-Cy5 and AMCA (7-amino-4-methylcoumarin-3-acetic acid). Recent reports indicate Rh 123 may also be a substrate of MRP1.
包装
5, 25, 100 mg in glass bottle